Bio-inspired artificial cilia with magnetic dynamic properties
Leilei SUN,Yongmei ZHENG()
Key Laboratory of Bio-Inspired Smart Interfacial Science and Technology of the Ministry of Education, School of Chemistry and Environment, Beihang University, Beijing 100191, China
Inspired by the structure and properties of natural cilia, we focused on a facile template-free approach to prepare magnetic artificial cilia grown on the substrate (glass, PDMS, or others). In an applied magnetic field, the cilia formed spontaneously and immediately from magnetic nanoparticles and elastomeric polymer in a liquid solvent by bottom-up self-assembly. The length of prepared cilia could be in the scale of millimeter and reach a high aspect ratio of even over 100. We studied the effect of the magnetic strength applied and the size of nanoparticles to get tunable scale of cilia. The cilia show reversibly bending in an external magnetic field and this bending actuation gave some important functions: to transport macroscopic nonmagnetic materials on the cilia and to mix liquids.
den Toonder J M J, Stark H, Khaderi S, . Artificial Cilia. Royal Society of Chemistry, 2013
2
Wang Y, Gao Y, Wyss H, . Back matter. Lab on a Chip, 2014, 14(17): 3427
3
Kokot G, Vilfan M, Osterman N, . Measurement of fluid flow generated by artificial cilia. Biomicrofluidics, 2011, 5(3): 034103
4
den Toonder J M J, Onck P R. Microfluidic manipulation with artificial/bioinspired cilia. Trends in Biotechnology, 2013, 31(2): 85–91
5
Bhattacharya A, Buxton G A, Usta O B, . Propulsion and trapping of microparticles by active cilia arrays. Langmuir, 2012, 28(6): 3217–3226
6
Khaderi S N, Craus C B, Hussong J, . Magnetically-actuated artificial cilia for microfluidic propulsion. Lab on a Chip, 2011, 11(12): 2002–2010
7
Maxey M R. Biomimetics and cilia propulsion. Journal of Fluid Mechanics, 2011, 678: 1–4
8
Alexeev A, Yeomans J M, Balazs A C. Designing synthetic, pumping cilia that switch the flow direction in microchannels.Langmuir, 2008, 24(21): 12102–12106
9
Toonder Jd, Bos F, Broer D, . Artificial cilia for active micro-fluidic mixing. Lab on a chip, 2008, 8(4): 533–541
10
Oh K, Chung J H, Devasia S, . Bio-mimetic silicone cilia for microfluidic manipulation. Lab on a Chip, 2009, 9(11): 1561–1566
11
Virta A, Timonen J V I, Ras R H A, . IEEE and J Robotics Society of 2012: 2012 IEEE/Rsj International Conference on Intelligent Robots and Systems (Iros), 1–6
12
Schroeder P, Schotter J, Shoshi A, . Artificial cilia of magnetically tagged polymer nanowires for biomimetic mechanosensing. Bioinspiration & Biomimetics, 2011, 6(4): 046007
13
Hussong J, Lindken R, Faulhammer P, . Cilia-driven particle and fluid transport over mucus-free mice tracheae. Journal of Biomechanics, 2013, 46(3): 593–598
14
Campbell C J, Grzybowski B A. Microfluidic mixers: from microfabricated to self-assembling devices. Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2004, 362(1818): 1069–1086
15
van Oosten C L, Bastiaansen C W M, Broer D J. Printed artificial cilia from liquid-crystal network actuators modularly driven by light. Nature Materials, 2009, 8(8): 677–682
16
Evans B A, Shields A R, Carroll R L, . Magnetically actuated nanorod arrays as biomimetic cilia. Nano Letters, 2007, 7(5): 1428–1434
17
Singh H, Laibinis P E, Hatton T A. Synthesis of flexible magnetic nanowires of permanently linked core-shell magnetic beads tethered to a glass surface patterned by microcontact printing. Nano Letters, 2005, 5(11): 2149–2154
18
Benkoski J J, Deacon R M, Land H B, . Dipolar assembly of ferromagnetic nanoparticles into magnetically driven artificial cilia. Soft Matter, 2010, 6(3): 602–609
19
Zhang D, Wang W, Peng F, . A bio-inspired inner-motile photocatalyst film: a magnetically actuated artificial cilia photocatalyst. Nanoscale, 2014, 6(10): 5516–5525
20
Rahbar M, Shannon L, Gray B L. Microfluidic active mixers employing ultra-high aspect-ratio rare-earth magnetic nano-composite polymer artificial cilia. Journal of Micromechanics and Microengineering, 2014, 24(2): 025003 (12 pages)
21
Timonen J V I, Johans C, Kontturi K, . A facile template-free approach to magnetodriven, multifunctional artificial cilia. ACS Applied Materials & Interfaces, 2010, 2(8): 2226–2230
