Please wait a minute...
Protein & Cell

ISSN 1674-800X

ISSN 1674-8018(Online)

CN 11-5886/Q

邮发代号 80-984

2019 Impact Factor: 10.164

Protein & Cell  2021, Vol. 12 Issue (10): 751-755   https://doi.org/10.1007/s13238-020-00807-6
  本期目录
Single cell RNA and immune repertoire profiling of COVID-19 patients reveal novel neutralizing antibody
Fang Li1, Meng Luo2, Wenyang Zhou2, Jinliang Li3, Xiyun Jin2, Zhaochun Xu2, Liran Juan2, Zheng Zhang3, Yuou Li3, Renqiang Liu1, Yiqun Li2, Chang Xu2, Kexin Ma2, Huimin Cao2, Jingwei Wang3, Pingping Wang2(), Zhigao Bu1(), Qinghua Jiang2,4()
1. State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150001, China
2. School of Life Science and Technology, Harbin Institute of Technology, Harbin 150000, China
3. Harbin Sixth Hospital, Harbin 150000, China
4. Key Laboratory of Biological Big Data (Harbin Institute of Technology), Ministry of Education, Harbin 150001, China
 全文: PDF(1673 KB)  
出版日期: 2021-11-18
Corresponding Author(s): Pingping Wang,Zhigao Bu,Qinghua Jiang   
 引用本文:   
. [J]. Protein & Cell, 2021, 12(10): 751-755.
Fang Li, Meng Luo, Wenyang Zhou, Jinliang Li, Xiyun Jin, Zhaochun Xu, Liran Juan, Zheng Zhang, Yuou Li, Renqiang Liu, Yiqun Li, Chang Xu, Kexin Ma, Huimin Cao, Jingwei Wang, Pingping Wang, Zhigao Bu, Qinghua Jiang. Single cell RNA and immune repertoire profiling of COVID-19 patients reveal novel neutralizing antibody. Protein Cell, 2021, 12(10): 751-755.
 链接本文:  
https://academic.hep.com.cn/pac/CN/10.1007/s13238-020-00807-6
https://academic.hep.com.cn/pac/CN/Y2021/V12/I10/751
1 J Cai, W Sun, J Huang, M Gamber, J Wu, G He (2020) Indirect virus transmission in cluster of COVID-19 cases, Wenzhou, China, 2020. Emerg Infect Dis J 26(6):1343–1345
https://doi.org/10.3201/eid2606.200412
2 Y Cao, B Su, X Guo, W Sun, Y Deng, L Bao, Q Zhu, X Zhang, Y Zheng, C Genget al. (2020) Potent neutralizing antibodies against SARS-CoV-2 identified by high-throughput single-cell sequencing of convalescent patients’ B cells. Cell 182:73-84.e16
https://doi.org/10.1016/j.cell.2020.05.025
3 AD Gitlin, L von Boehmer, A Gazumyan, Z Shulman, TY Oliveira, MC Nussenzweig (2016) Independent roles of switching and hypermutation in the development and persistence of B lymphocyte memory. Immunity 44:769–781
https://doi.org/10.1016/j.immuni.2016.01.011
4 X Hu, J Zhang, J Wang, J Fu, T Li, X Zheng, B Wang, S Gu, P Jiang, J Fanet al. (2019) Landscape of B cell immunity and related immune evasion in human cancers. Nat Genet 51:560–567
https://doi.org/10.1038/s41588-018-0339-x
5 Z Lv, Y-Q Deng, Q Ye, L Cao, C-Y Sun, C Fan, W Huang , S Sun, Y Sun, L Zhuet al. (2020) Structural basis for neutralization of SARSCoV-2 and SARS-CoV by a potent therapeutic antibody. Science 369:1505–1509
https://doi.org/10.1126/science.abc5881
6 G Palladino, K Mozdzanowska, G Washko, W Gerhard (1995) Virusneutralizing antibodies of immunoglobulin G (IgG) but not of IgM or IgA isotypes can cure influenza virus pneumonia in SCID mice. J Virol 69:2075–2081
https://doi.org/10.1128/JVI.69.4.2075-2081.1995
7 I Thevarajan, THO Nguyen, M Koutsakos, J Druce, L Caly, CE van de Sandt, X Jia, S Nicholson, M Catton, B Cowieet al. (2020) Breadth of concomitant immune responses prior to patient recovery: a case report of non-severe COVID-19. Nat Med 26:453–455
https://doi.org/10.1038/s41591-020-0819-2
8 J Wang, L Shuai, C Wang, R Liu, X He, X Zhang, Z Sun, D Shan, J Ge, X Wanget al.(2020) Mouse-adapted SARS-CoV-2 replicates efficiently in the upper and lower respiratory tract of BALB/c and C57BL/6J mice. Protein Cell 11(10):1–7
https://doi.org/10.1007/s13238-020-00767-x
9 S Wu, G Zhong, J Zhang, L Shuai, Z Zhang, Z Wen, B Wang, Z Zhao, X Song, Y Chenet al.(2020) A single dose of an adenovirusvectored vaccine provides protection against SARS-CoV-2 challenge. Nat Commun 11:4081
https://doi.org/10.1038/s41467-020-17972-1
10 Q Zou, Q Hu, M Guo, G Wang (2015) HAlign: fast multiple similar DNA/RNA sequence alignment based on the centre star strategy. Bioinformatics 31:2475–2481
https://doi.org/10.1093/bioinformatics/btv177
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed