|
|
Cushing’s syndrome during pregnancy caused by adrenal cortical adenoma: a case report and literature review |
Wei Wang(),Fengyi Yuan,Dan Xu |
Department of Endocrinology and Metabolism, Shenzhen People’s Hospital, Shenzhen 518020, China |
|
|
Abstract Cushing’s syndrome (CS) during pregnancy is a rare condition with significant maternal and fetal complications. A case of CS during the third trimester of pregnancy secondary to adrenocortical adenoma was reported. Literature review revealed the disadvantages of different treatments in this period. Besides the conservative treatment, surgery is recommended for CS during the third trimester of pregnancy secondary to adrenal adenoma, if an experienced surgeon is available.
|
Keywords
Cushing’s syndrome
pregnancy
adrenocortical adenoma
|
Corresponding Author(s):
Wei Wang
|
Just Accepted Date: 10 July 2015
Online First Date: 21 August 2015
Issue Date: 26 August 2015
|
|
1 |
Lekarev O, New MI. Adrenal disease in pregnancy. Best Pract Res Clin Endocrinol Metab 2011; 25(6): 959–973
https://doi.org/10.1016/j.beem.2011.08.004
pmid: 22115169
|
2 |
Pickard J, Jochen AL, Sadur CN, Hofeldt FD. Cushing’s syndrome in pregnancy. Obstet Gynecol Surv 1990; 45(2): 87–93
https://doi.org/10.1097/00006254-199002000-00002
pmid: 2405312
|
3 |
Kamiya Y, Okada M, Yoneyama A, Jin-no Y, Hibino T, Watanabe O, Kajiura S, Suzuki Y, Iwata H, Kobayashi S. Surgical successful treatment of Cushing’s syndrome in a pregnant patient complicated with severe cardiac involvement. Endocr J 1998; 45(4): 499–504
https://doi.org/10.1507/endocrj.45.499
pmid: 9881899
|
4 |
Nakashima YM, Itonaga Y, Inoue H, Takahashi S. Pulmonary edema after laparoscopic adrenalectomy in a pregnant patient with Cushing’s syndrome. J Anesth 2000; 14(3): 157–159
https://doi.org/10.1007/s005400070026
pmid: 14564585
|
5 |
Aishima M, Tanaka M, Haraoka M, Naito S. Retroperitoneal laparoscopic adrenalectomy in a pregnant woman with Cushing’s syndrome. J Urol 2000; 164(3 Pt 1): 770–771
pmid: 10953144
|
6 |
Shaw JA, Pearson DW, Krukowski ZH, Fisher PM, Bevan JS. Cushing’s syndrome during pregnancy: curative adrenalectomy at 31 weeks gestation. Eur J Obstet Gynecol Reprod Biol 2002; 105(2): 189–191
https://doi.org/10.1016/S0301-2115(02)00148-3
pmid: 12381486
|
7 |
Tejura H, Weiner J, Gibby O, O’Leary AJ, Avasarala S. Cushing’s syndrome in pregnancy. J Obstet Gynaecol 2005; 25(7): 713–714
https://doi.org/10.1080/01443610500303648
pmid: 16263550
|
8 |
Sammour RN, Saiegh L, Matter I, Gonen R, Shechner C, Cohen M, Ohel G, Dickstein G. Adrenalectomy for adrenocortical adenoma causing Cushing’s syndrome in pregnancy: a case report and review of literature. Eur J Obstet Gynecol Reprod Biol 2012; 165(1): 1–7
https://doi.org/10.1016/j.ejogrb.2012.05.030
pmid: 22698457
|
9 |
Chang I, Cha HH, Kim JH, Choi SJ, Oh SY, Roh CR. Cushing syndrome in pregnancy secondary to adrenal adenoma. Obstet Gynecol Sci 2013; 56(6): 400–403
https://doi.org/10.5468/ogs.2013.56.6.400
pmid: 24396819
|
10 |
Lo KW, Lau TK. Cushing’s syndrome in pregnancy secondary to adrenal adenoma. A case report and literature review. Gynecol Obstet Invest 1998; 45(3): 209–212
https://doi.org/10.1159/000009958
pmid: 9565149
|
11 |
Handler J. Cushing’s syndrome with uncontrolled hypertension, occasional hypokalemia, and two pregnancies. J Clin Hypertens (Greenwich)2010; 12(7): 516–521
pmid: 20629814
|
12 |
Holgado-Galicia MV, Magno JD, Acelajado-Valdenor C, Isip-Tan IT, Lim-Abrahan MA. Cushing’s syndrome in pregnancy. BMJ Case Rep 2011; 2011: bcr0120113720
https://doi.org/10.1136/bcr.01.2011.3720
pmid: 22696666
|
13 |
Choi WJ, Jung TS, Paik WY. Cushing’s syndrome in pregnancy with a severe maternal complication: a case report. J Obstet Gynaecol Res 2011; 37(2): 163–167
https://doi.org/10.1111/j.1447-0756.2010.01339.x
pmid: 21159041
|
14 |
Borna S, Akbari S, Eftekhar T, Mostaan F. Cushing’s syndrome during pregnancy secondary to adrenal adenoma. Acta Med Iran 2012; 50(1): 76–78
pmid: 22267384
|
15 |
Kita M, Sakalidou M, Saratzis A, Ioannis S, Avramidis A. Cushing’s syndrome in pregnancy: report of a case and review of the literature. Hormones (Athens)2007; 6(3): 242–246
pmid: 17724009
|
16 |
Al Banna R, Husain A, Al Aali J, Ebrahim K, Mohammed. Reversible Cushing dilated cardiomyopathy mimicking peripartum cardiomyopathy with successful subsequent pregnancy. BMJ Case Rep 2011; 2011: bcr0920114825
https://doi.org/10.1136/bcr.09.2011.4825
pmid: 22674115
|
17 |
Kim HG, Lee KH, Je GH, Han MS. A case of Cushing’s syndrome in pregnancy secondary to an adrenal cortical adenoma. J Korean Med Sci 2003; 18(3): 444–446
https://doi.org/10.3346/jkms.2003.18.3.444
pmid: 12808338
|
18 |
Hunt AB, McCONAHEY WM. Pregnancy associated with diseases of the adrenal glands. Am J Obstet Gynecol 1953; 66(5): 970–987
pmid: 13104499
|
19 |
Lindsay JR, Jonklaas J, Oldfield EH, Nieman LK. Cushing’s syndrome during pregnancy: personal experience and review of the literature. J Clin Endocrinol Metab 2005; 90(5): 3077–3083
https://doi.org/10.1210/jc.2004-2361
pmid: 15705919
|
20 |
Vilar L, Freitas MC, Lima LH, Lyra R, Kater CE. Cushing’s syndrome in pregnancy: an overview. Arq Bras Endocrinol Metabol 2007; 51(8): 1293–1302
https://doi.org/10.1590/S0004-27302007000800015
pmid: 18209867
|
21 |
Cohade C, Broussaud S, Louiset E, Bennet A, Huyghe E, Caron P. Ectopic Cushing’s syndrome due to a pheochromocytoma: a new case in the post-partum and review of literature. Gynecol Endocrinol 2009; 25(9): 624–627
https://doi.org/10.1080/09513590903015411
pmid: 19591016
|
22 |
Rask E, Schvarcz E, Hellman P, Hennings J, Karlsson FA, Rao CV. Adrenocorticotropin-independent Cushing’s syndrome in pregnancy related to overexpression of adrenal luteinizing hormone/human chorionic gonadotropin receptors. J Endocrinol Invest 2009; 32(4): 313–316
https://doi.org/10.1007/BF03345718
pmid: 19636197
|
23 |
Terhune KP, Jagasia S, Blevins LS Jr, Phay JE. Diagnostic and therapeutic dilemmas of hypercortisolemia during pregnancy: a case report. Am Surg 2009; 75(3): 232–234
pmid: 19350859
|
24 |
Casonato A, Daidone V, Pontara E, Albiger N, Cattini MG, Scaroni C. Hypercortisolism and pregnancy upregulate von Willebrand factor through different mechanisms: report on a pregnant patient with Cushing’s syndrome. Blood Coagul Fibrinolysis 2010; 21(5): 476–479
https://doi.org/10.1097/MBC.0b013e328338dbba
pmid: 20614575
|
25 |
Pollack RP, Brett EM. Adrenocorticotropic hormone-independent Cushing syndrome manifesting during pregnancy. Endocr Pract 2010; 16(2): 260–263
https://doi.org/10.4158/EP09232.CR
pmid: 20061276
|
26 |
Asicioglu E, Gonenli G, Kahveci A, Yildizeli B, Deyneli O, Yavuz D, Yuksel M, Akalin S. Thymic neuroendocrine carcinoma presenting as cushing’s syndrome: treatment with octreotide combined with surgery and radiotherapy. Onkologie 2011; 34(1-2): 46–49
https://doi.org/10.1159/000323348
pmid: 21346385
|
27 |
Bednarek-Tupikowska G, Kubicka E, Sicińska-Werner T, Kazimierczak A, Winowski J, Tupikowska M, Janczyszyn M, Bolanowski M. A case of Cushing’s syndrome in pregnancy. Endokrynol Pol 2011; 62(2): 181–185
pmid: 21528482
|
28 |
Boronat M, Marrero D, López-Plasencia Y, Barber M, Schamann Y, Nóvoa FJ. Successful outcome of pregnancy in a patient with Cushing’s disease under treatment with ketoconazole during the first trimester of gestation. Gynecol Endocrinol 2011; 27(9): 675–677
https://doi.org/10.3109/09513590.2010.521268
pmid: 20923280
|
29 |
Toutounchi S, Makowska A, Krajewska E, Fiszer P, Cie?la W, Pogorzelski R, Bartnik A, Wielgo? M, Bar-Andziak E, Skórski M. Laparoscopic treatment of Cushing’s syndrome in a woman in late pregnancy- a case presentation. Wideochir Inne Tech Malo Inwazyjne 2011; 6(4): 261–263
https://doi.org/10.5114/wiitm.2011.26263
pmid: 23255991
|
30 |
Achong N, D’Emden M, Fagermo N, Mortimer R. Pregnancy-induced Cushing’s syndrome in recurrent pregnancies: case report and literature review. Aust N Z J Obstet Gynaecol 2012; 52(1): 96–100
https://doi.org/10.1111/j.1479-828X.2011.01388.x
pmid: 22188308
|
31 |
Gopal RA, Acharya SV, Bandgar TR, Menon PS, Shah NS. Cushing disease with pregnancy. Gynecol Endocrinol 2012; 28(7): 533–535
https://doi.org/10.3109/09513590.2011.632789
pmid: 22551350
|
32 |
Homer L, Viatge M, Gayet FX, Laurent Y, Kerlan V. Cushing syndrome and pregnancy: a propos of a malignant adrenocortical carcinoma. Gynecol Obstet Fertil 2012; 40(3): e1–e4
https://doi.org/10.1016/j.gyobfe.2011.07.053
pmid: 22342109
|
33 |
Kimura Y, Okuyama K, Mitsui K, Tamaki F, Nonaka A, Matsukawa T. Anesthetic management for laparoscopic adrenalectomy in a pregnant patient with Cushing’s syndrome. Masui 2012; 61(6): 605–609
pmid: 22746024
|
34 |
Garla V, Kheetan R, Saleem T. Cushing’s syndrome in pregnancy: a diagnostic conundrum. W V Med J 2013; 109(6): 34–36
pmid: 24371863
|
35 |
Lim WH, Torpy DJ, Jeffries WS. The medical management of Cushing’s syndrome during pregnancy. Eur J Obstet Gynecol Reprod Biol 2013; 168(1): 1–6
https://doi.org/10.1016/j.ejogrb.2012.12.015
pmid: 23305861
|
36 |
Xu JJ, Wang YJ, Shan LZ, Gu W, Zeng WH. Recurrent ACTH-independent Cushing’s syndrome in multiple pregnancies. Gynecol Endocrinol 2013; 29(4): 309–310
https://doi.org/10.3109/09513590.2012.743014
pmid: 23323736
|
37 |
Williams RH, Melmed S. Williams Textbook of Endocrinology. Philadelphia: Elsevier/Saunders, 2011: online resource (1920 p.)
|
38 |
Lindsay JR, Nieman LK. Adrenal disorders in pregnancy. Endocrinol Metab Clin North Am 2006; 35(1): 1–20, v
https://doi.org/10.1016/j.ecl.2005.09.010
pmid: 16310640
|
39 |
Lindsay JR, Nieman LK. The hypothalamic-pituitary-adrenal axis in pregnancy: challenges in disease detection and treatment. Endocr Rev 2005; 26(6): 775–799
https://doi.org/10.1210/er.2004-0025
pmid: 15827110
|
40 |
Polli N, Pecori Giraldi F, Cavagnini F. Cushing’s syndrome in pregnancy. J Endocrinol Invest 2003; 26(10): 1045–1050
https://doi.org/10.1007/BF03348206
pmid: 14759081
|
|
Viewed |
|
|
|
Full text
|
|
|
|
|
Abstract
|
|
|
|
|
Cited |
|
|
|
|
|
Shared |
|
|
|
|
|
Discussed |
|
|
|
|