|
|
|
CONET: a virtual human system-centered platform for drug discovery |
Doheon LEE( ) |
| Bio-Synergy National Research Center, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 305-701, Korea |
|
|
|
|
|
|
Just Accepted Date: 04 August 2017
Online First Date: 22 September 2017
Issue Date: 12 January 2018
|
|
| 1 |
Harvey A L. Natural products in drug discovery. Drug Discovery Today, 2008, 13(19): 894–901
https://doi.org/10.1016/j.drudis.2008.07.004
|
| 2 |
Park B K, Boobis A, Clarke S, Goldring C E P, Jones D, Kenna J G, Lambert C, Laverty H G, Naisbitt D J, Nelson S, Nicoll-Griffith D A, Obach R S, Routledge P, Smith D A, Tweedie D J, Vermeulen N, Williams D P, Wilson I D, Baillie T A. Managing the challenge of chemically reactive metabolites in drug development. Nature Reviews Drug Discovery, 2011, 10(4): 292–306
https://doi.org/10.1038/nrd3408
|
| 3 |
Nelander S, Wang W Q, Nilsson B, She Q B, Pratilas C, Rosen N, Gennemark P, Sander C. Models from experiments: combinatorial drug perturbations of cancer cells. Molecular Systems Biology, 2008, 4(1): 216
https://doi.org/10.1038/msb.2008.53
|
| 4 |
Langley G R, Adcock I M, Busquet F, Crofton K M, Csernok E, Giese C, Heinonen T, Herrmann K, Hofmann-Apitius M, Landesmann B, Marshall L J, Mclvor E, Muotri A R, Noor F, Schutte K, Seidle T, Van de Stolpe A, Esch H V, Willett C, Woszczek G. Towards a 21st-century roadmap for biomedical research and drug discovery: consensus report and recommendations. Drug Discovery Today, 2016, 22(2): 327–339
https://doi.org/10.1016/j.drudis.2016.10.011
|
| 5 |
Hwang W, Hwang Y, Lee S, Lee D. Rule-based multi-scale simulation for drug effect pathway analysis. BMC Medical Informatics and Decision Making, 2013, 13(1): 1–9
https://doi.org/10.1186/1472-6947-13-S1-S4
|
| 6 |
Yu H, Jung J, Yoon S, Kwon M, Bae S, Yim S, Lee J, Kim S, Kang Y, Lee D. CODA: integratingmulti-level context-oriented directed associations for analysis of drug effects. Scientific Reports, 2017, 7: 7519
https://doi.org/10.1038/s41598-017-07448-6
|
|
Viewed |
|
|
|
Full text
|
|
|
|
|
Abstract
|
|
|
|
|
Cited |
|
|
|
|
| |
Shared |
|
|
|
|
| |
Discussed |
|
|
|
|