The four decades since reform and opening up have seen dramatic changes in China’s higher education system. Focusing on international dimensions, the analysis supports the view that reform and opening up was not merely an economic and political reform, but an opening of the mind to the outside world, after the disaster of the Cultural Revolution. But it is important to be reminded that China’s relations with the outside world have a much longer history, with the spread of Confucian ideas to East and Southeast Asia, and the importation of Buddhism from ancient India; both during the Tang dynasty. The article points to key ongoing debates in China about the extent to which it can incorporate ideas from outside, while still retaining a Chinese essence. The rise of China as a knowledge hub and destination for international students is also charted, and the prospects for further development are assessed.