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Outline and computational approaches of protein misfolding |
Xin LIU( ) |
| The State Key Laboratory of Nonlinear Mechanics, Institute of Mechanics, Chinese Academy of Sciences, Beijing 100190, China |
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Abstract Protein misfolding is a general causation of classical conformational diseases and many pathogenic changes that are the result of structural conversion. Here I review recent progress in clinical and computational approaches for each stage of the misfolding process, aiming to present readers an outline for swift comprehension of this field.
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| Keywords
computational approaches
protein misfolding
conformational diseases
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Corresponding Author(s):
LIU Xin,Email:liuxin@lnm.imech.ac.cn
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Issue Date: 01 June 2010
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