|
|
|
Personalized biomedical devices & systems for healthcare applications |
I-Ming CHEN( ), Soo Jay PHEE, Zhiqiang LUO, Chee Kian LIM |
| School of Mechanical and Aerospace Engineering, Nanyang Technological University, Singapore, Singapore |
|
|
|
|
Abstract With the advancement in micro- and nanotechnology, electromechanical components and systems are getting smaller and smaller and gradually can be applied to the human as portable, mobile and even wearable devices. Healthcare industry have started to benefit from this technology trend by providing more and more miniature biomedical devices for personalized medical treatments in order to obtain better and more accurate outcome. This article introduces some recent development in non-intrusive and intrusive biomedical devices resulted from the advancement of niche miniature sensors and actuators, namely, wearable biomedical sensors, wearable haptic devices, and ingestible medical capsules. The development of these devices requires carful integration of knowledge and people from many different disciplines like medicine, electronics, mechanics, and design. Furthermore, designing affordable devices and systems to benefit all mankind is a great challenge ahead. The multi-disciplinary nature of the R&D effort in this area provides a new perspective for the future mechanical engineers.
|
| Keywords
personalized medical devices
wearable sensor
haptic device
ingestible medical capsule
|
|
Corresponding Author(s):
CHEN I-Ming,Email:michen@ntu.edu.sg
|
|
Issue Date: 05 March 2011
|
|
| 1 |
Tr?ster G. The agenda of wearable healthcare. In: Haux R, Kulikowski C, eds. IMIA Yearbook of Medical Informatics 2005: Ubiquitous Health Care Systems. 2005, 125-138
|
| 2 |
Reid P P, Compton W D, Grossman J H, Fanjiang G, eds. Building a Better delivery System: A New Engineering/Health Care Partnership. National Academy Press , 2005
|
| 3 |
Habetha J. The MyHeart project – Fighting cardiovascular diseases by prevention and early diagnosis, In: Proceeding 28th Annual International IEEE EMBS Conference, 2006, 6746-6749
|
| 4 |
Milenkovic A, Otto C, Jovanov E. Wireless sensor networks for personal health monitoring: Issues and an implementation. Computer Communications , 2006, 29(13-14): 2521-2533
doi: 10.1016/j.comcom.2006.02.011
|
| 5 |
Zephyr. http://www.zephyr-technology.com/bioharness-bt.html
|
| 6 |
IEEE standard for safety levels with respect to human exposure to radio frequency electromagnetic fields, 3 kHz to 300 GHz. In IEEE Std C95.1 , 2006
|
| 7 |
Ren H, Meng M Q H, Chen X. Physiological information acquisition through wireless biomedical sensor networks. In: Proceedings of the 2005 IEEE International Conference on Information Acquisition, Hong Kong and Macau, China, 2005
|
| 8 |
Yang G Z, ed. Body Sensor Networks. London, Springer-Verlag2006
|
| 9 |
Park S, Jayaraman S. E-health and quality of life: The role of the wearable motherboard. In: Lymberis A, DeRossi D, eds. Wearable eHealth Systems for Personalised Health Management , IOS Press, Amsterdam, 2004, 239-252
|
| 10 |
Lukowicz P, Kirstein T, Tr?ster G.Wearable systems for health care applications. Methods of Information in Medicine, 2004, 43(3): 232-238
|
| 11 |
Cottet D, Grzyb J, Kirstein T, Tr?ster G. Electrical characterization of textile transmission lines. IEEE Transactions on Advanced Packaging , 2003, 26(2): 182-190
doi: 10.1109/TADVP.2003.817329
|
| 12 |
Scilingo E P, Lorussi F, Mazzoldi A, De Rossi D. Strain-sensing fabrics for wearable kinaesthetic-like systems. IEEE Sensors Journal , 2003, 3(4): 460-467
doi: 10.1109/JSEN.2003.815771
|
| 13 |
Dunne L E, Brady S, Smyth B, Diamond D. Initial development and testing of a novel foam-based pressure sensor for wearable sensing. Journal of Neuroengineering and Rehabilitation , 2005, 2(4): 1-7
pmid:15730560
|
| 14 |
Otto C, Milenkovic A, Sanders C, Jovanov E. System architecture of a wireless body area sensor network for ubiquitous health monitoring. Journal of Mobile Multimedia , 2006, 1(4): 307-326
|
| 15 |
Hill J L. System architecture for wireless sensor networks. Dissertation for the Doctoral Degree. Berkeley: University of California, 2003
|
| 16 |
Cho H C, Marbán E. Biological therapies for cardiac arrhythmias: can genes and cells replace drugs and devices? Circulation Research , 2010, 106(4): 674-685
doi: 10.1161/CIRCRESAHA.109.212936 pmid:20203316
|
| 17 |
GivenImage. http://www.givenimaging.com/en-us/Pages/GivenWelcomePage.aspx
|
| 18 |
Vicon. http://www.vicon.com
|
| 19 |
Gypsy 7. http://www.metamotion.com/gypsy/gypsy-motion-capture-system.htm
|
| 20 |
Donno M, Palange E, Di Nicola F, Bucci G, Ciancetta F. A new flexible optical fiber goniometer for dynamic angular, measurements: application to human joint movement monitoring. IEEE Transactions on Instrumentation and Measurement , 2008, 57(8): 1614-1620
doi: 10.1109/TIM.2008.925336
|
| 21 |
De Rossi D, Carpi F, Lorussi F, Scilingo E P, Tognetti A. Electroactive fabrics and wearable manmachine interfaces. In: Tao X, ed. Wearable Electronics and Photonics. Textiles: Woodhead Publishing, 2005, 59-80
|
| 22 |
Intersense. http://www.intersense.com
|
| 23 |
Eltaib M E H, Hewit J R. Tactile sensing technology for minimal access surgery- a review. Mechatronics , 2003, 13(10): 1163-1177
doi: 10.1016/S0957-4158(03)00048-5
|
| 24 |
Coles T, Meglan D, John N W. The role of haptics in medical training simulators: A survey of the state-of-the-art. IEEE Transactions on Haptics , 2010
|
| 25 |
Lee M H, Nicholls H R. Tactile sensing for mechatronics-a state of the art survey. Mechatronics , 1999, 9(1): 1-31
doi: 10.1016/S0957-4158(98)00045-2
|
| 26 |
King C H, Culjat M O, Franco M L, Lewis C E, Grundfest W S, Bisley J W. Tactile feedback induces reduced grasping force in robot-assisted surgery . IEEE Transactions on Haptics , 2009, 2(2): 103-110
doi: 10.1109/TOH.2009.4
|
| 27 |
Tanaka M, Lévêque J L, Tagami H, Kikuchi K, Chonan S. The “haptic finger”- a new device for monitoring skin condition. Skin Research and Technology , 2003, 9(2): 131-136
doi: 10.1034/j.1600-0846.2003.00031.x pmid:12709131
|
| 28 |
Yeatman E M, Mitcheson P D. Energy scavenging. In: Yang G Z, ed. Body Sensor Networks. Springer , 2006, 183-217
|
| 29 |
Glukhovsky A, Iddan G J, Meron G.US2005228259, 2005
|
| 30 |
Koplow M, Chen A, Steingart D, Wright P K, Evans J W. Thick film thermoelectric energy harvesting systems for biomedical applications. International Workshop on Wearable and Implantable Body Sensor Networks (BSN 2008), 2008, 322-325
|
| 31 |
Yoo H J, Song S J, Cho N, Kim H J. Low energy on-body communication for BSN. Workshop of Body Sensor Networks , 2007, 15-28
|
| 32 |
Krause A, Smailagic A, Siewiorek D P. Context-aware mobile computing: Learning context-dependent personal preferences from a wearable sensor array. IEEE Transactions on Mobile Computing , 2006, 5(2): 113-127
doi: 10.1109/TMC.2006.18
|
| 33 |
Junker H, Lukowicz P. Tr?ster G. Sampling frequency, signal resolution and the accuracy of wearable context recognition systems. In: Proceedings of 8th International Symposium on Wearable Computers (ISWC) , 2004
|
| 34 |
Guo T, Zhang L, Liu W, Zhou Z A. Novel solution to power problems in implanted biosensor networks. In: Proceedings of 28th Annual International Conference of IEEE Engineering in Medicine and Biology Society , 2006, 5952-5955
|
| 35 |
Burdea G C. Virtual rehabilitation—benefits and challenges. Methods of Information in Medicine , 2003, 42(5): 519-523
pmid:14654886
|
| 36 |
Sveistrup H. Motor rehabilitation using virtual reality. Journal of Neuroengineering and Rehabilitation , 2004, 1(1): 10
doi: 10.1186/1743-0003-1-10 pmid:15679945
|
| 37 |
Weiss P L, Kizony R, Feintuch U, Katz N. Virtual reality in neurorehabilitation. In: M E Selzer, L Cohen, F H Gage, S C larke, P W Duncan . (Editors). Textbook of Neural Repair and Rehabilitation . Cambridge: University Press, 2006, 182-197
|
| 38 |
Gunduz A. Human motor control through electrocorticographic brain machine interfaces, , 2008
|
| 39 |
Oviatt S L. Advances in robust multimodal interface design. IEEE Computer Graphics and Applications , 2003, 23(5): 62-68
doi: 10.1109/MCG.2003.1231179
|
| 40 |
Carlson M. Understanding the “Mother’s Touch”. Harvard Mahoney Neuroscience Institute Letter to the Brain , 1998, 7(1): 12-13
|
| 41 |
Filed T. Infants’ need for touch. Human Development , 2002, 45(2): 100-103
doi: 10.1159/000048156
|
| 42 |
Harlow H F. The nature of love.http://psychclassics.yorku.ca/Harlow/love.htm
|
| 43 |
Goleman D. The experience of touch: Research points to a critical role. New York Times, February 2 , 1988
|
| 44 |
Chouvardas V G, Miliou A N, Hatalis M K. Tactile displays: overview and recent advances. Displays , 2008, 29(3): 185-194
doi: 10.1016/j.displa.2007.07.003
|
| 45 |
Toney A, Dunne L, Thomas B H, Ashdown S P. A shoulder pad insert vibrotactile display. In: Proceedings of the Seventh IEEE International Symposium on Wearable Computers (ISWC03), 2003, 35-44
|
| 46 |
Cholewiak R W, Collins A A. Vibrotactile localization on the arm: effects of place, space, and age. Perception & Psychophysics , 2003, 65(7): 1058-1077
pmid:14674633
|
| 47 |
Kyung K U, Ahn M, Kwon D S, Srinivasan M. Perceptual and biomechanical frequency response of human skin: implication for design of tactile displays. In: Proceeding of First Joint Eurohaptics Conference and Symposium on Haptic Interfaces for Virtual Environment and Teleoperator Systems (WHC 2005), 2005, 96-101
|
| 48 |
Lieberman J, Breazeal C. TIKL: Development of a wearable vibrotactile feedback suit for improved human motor learning. IEEE Transactions on Robotics , 2007, 23(5): 919-926
doi: 10.1109/TRO.2007.907481
|
| 49 |
Lindeman R W, Yanagida Y, Hosaka K, Abe S. The TactaPack: A wireless sensor/actuator package for physical therapy applications. In: Proceeding of 14th Symposium on Haptic Interfaces for Virtual Environment and Teleoperator Systems, 2006, 337-341
|
| 50 |
Markow T, Ramakrishnan N, Huang K, Starner T, Eicholtz M, Garrett S, Profita H, Scarlata A, Backus D. Mobile music touch: vibration stimulus in hand rehabilitation. In: Proceeding of 4th International Conference on Pervasive Computing Technologies for Healthcare, 2010, 1-8
|
| 51 |
De Rossi D, Carpi F, Lorussi F, Scilingo E P, Tognetti A. Wearable kinesthetic systems and emerging technologies in actuation for upperlimb neurorehabilitation. In: Proceeding of International Conference of the IEEE Engineering in Medicine and Biology Society, 2009, 6830-6833
|
| 52 |
Bonanni L, Vaucelle C, Lieberman J, Zuckerman O. TapTap: A haptic wearable for asynchronous distributed touch therapy. In: Extended Abstracts on Human Factors in Computing, 2006, 580-585
|
| 53 |
Vaucelle C, Abbas Y. Touch: Sensitive apparel. In: Extended Abstracts on Human Factors in Computing Systems, 2007, 2723-2728
|
| 54 |
Koo I M, Jung K, Koo J C, Nam J D, Lee Y K, Choi H R. Development of soft-actuator-based wearable tactile display. IEEE Transactions on Robotics , 2008, 24(3): 549-558
doi: 10.1109/TRO.2008.921561
|
| 55 |
Bark K, Wheeler J, Shull P, Savall J, Cutkosky M. Rotational skin stretch feedback: A wearable haptic display for motion. IEEE Transactions on Haptics, 2010, 166-176
|
| 56 |
Wheeler J, Bark K, Savall J, Cutkosky M. Investigation of rotational skin stretch for proprioceptive feedback with application to myoelectric systems. IEEE Transactions on Neural Systems and Rehabilitation Engineering , 2010, 18(1): 58-66
doi: 10.1109/TNSRE.2009.2039602 pmid:20071271
|
| 57 |
Iddan G, Meron G, Glukhovsky A, Swain P. Wireless capsule endoscopy. Nature , 2000, 405(6785): 417
doi: 10.1038/35013140 pmid:10839527
|
| 58 |
Pillcam. http://www.givenimaging.com
|
| 59 |
Endocapsule, http://www.olympusamerica.com/msg_section/index.asp
|
| 60 |
MicroCam. http://www.intromedic.com
|
| 61 |
OMOM. http://www.jinshangroup.com
|
| 62 |
Klauser A G, Schindlbeck N E, Müller-Lissner S A. Symptoms in gastro-oesophageal reflux disease. Lancet , 1990, 335(8683): 205-208
doi: 10.1016/0140-6736(90)90287-F pmid:1967675
|
| 63 |
Mackay R S, Jacobson B. Endoradiosonde. Nature , 1957, 179(4572): 1239-1240
doi: 10.1038/1791239a0 pmid:13440945
|
| 64 |
SmartPill. http://www.smartpillcorp.com
|
| 65 |
Parr A F, Sandefer E P, Wissel P, McCartney M, McClain C, Ryo U Y, Digenis G A. Evaluation of the feasibility and use of a prototype remote drug delivery capsule (RDDC) for non-invasive regional drug absorption studies in the GI tract of man and beagle dog. Pharmaceutical Research , 1999, 16(2): 266-271
doi: 10.1023/A:1018884510163 pmid:10100313
|
| 66 |
Wilding I I, Hirst P, Connor A. Development of a new engineering-based capsule for human drug absorption studies. Pharmaceutical Science & Technology Today , 2000, 3(11): 385-392
doi: 10.1016/S1461-5347(00)00311-4 pmid:11091162
|
| 67 |
Kong K C, Cha J, Jeon D, Cho D I. A rotational micro biopsy device for the capsule endoscope. In: Proceeding of IEEE/RSJ International Conference on Intelligent Robots and Systems, Alberta, Canada, 2005, 1839-1843
|
| 68 |
Park S, Koo K i, Bang S M, Park J Y, Song S Y, Cho D D. Cho D D. A novel microactuator for microbiopsy in capsular endoscopes. Journal of Micromechanics and Microengineering , 2008, 18(2): 25-32
doi: 10.1088/0960-1317/18/2/025032
|
| 69 |
Cavallotti C, Piccigalloa M, Susiloa E, Valdastria P, Menciassia A. Paolo Dario. An integrated vision system with autofocus for wireless capsular endoscopy. Sensors and Actuators. A, Physical , 2009, 156(1): 72-78
doi: 10.1016/j.sna.2009.01.028
|
| 70 |
Rasouli M, Kencana A P, Van A H, Kiat E, Lai J C Y, Phee L S J. Wireless capsule endoscopes for enhanced diagnostic inspection of gastrointestinal tract. In: Proceeding of IEEE Conference on Robotics Automation and Mechatronics, Singapore, 2010, 68-71
|
| 71 |
Kim H M, Yang S, Kim J, Park S, Cho J H, Park J Y, Kim T S, Yoon E S, Song S Y, Bang S. Active locomotion of a paddling-based capsule endoscope in an in vitro and in vivo experiment (with videos). Gastrointestinal Endoscopy , 2010, 72(2): 381-387
doi: 10.1016/j.gie.2009.12.058 pmid:20497903
|
| 72 |
Quirini M, Menciassi A, Scapellato S, Dario P, Rieber F, Ho C N, Schostek S, Schurr M O. Feasibility proof of a legged locomotion capsule for the GI tract. Gastrointestinal Endoscopy , 2008, 67(7): 1153-1158
doi: 10.1016/j.gie.2007.11.052 pmid:18513557
|
| 73 |
Bradley P D. An ultra low power, high performance Medical Implant Communication System (MICS) transceiver for implantable devices. In: Proceeding of IEEE Biomedical Circuits and Systems Conference, 2006, 158-161
|
| 74 |
Chen X, Zhang X, Zhang L, Li X, Qi N, Jiang H, Wang Z. A wireless capsule endoscope system with low-power controlling and processing ASIC. IEEE Transactions on Biomedical Circuits and Systems , 2009, 3(1): 11-22
doi: 10.1109/TBCAS.2008.2006493
|
| 75 |
Chi B, Yao J, Han S, Xie X, Li G, Wang Z. A 2.4 GHz low power wireless transceiver analog front-end for endoscopy capsule system. Analog Integrated Circuits and Signal Processing , 2007, 51(2): 59-71
doi: 10.1007/s10470-007-9036-x
|
| 76 |
Swain P. The future of wireless capsule endoscopy. World Journal of Gastroenterology , 2008, 14(26): 4142-4145
doi: 10.3748/wjg.14.4142 pmid:18636658
|
| 77 |
Guanying M, Guozheng Y, Xiu H. Power transmission for gastrointestinal microsystems using inductive coupling. Physiological Measurement , 2007, 28(3): N9-N18
doi: 10.1088/0967-3334/28/3/N01 pmid:17322587
|
| 78 |
Lenaerts B, Puers R. Omnidirectional Inductive Powering for Biomedical implants. Springer Netherlands, 2009
|
| 79 |
Fischer D, Schreiber R, Levi D, Eliakim R. Capsule endoscopy: the localization system. Gastrointestinal Endoscopy Clinics of North America , 2004, 14(1): 25-31
doi: 10.1016/j.giec.2003.10.020 pmid:15062377
|
| 80 |
Hu C, Meng M, Mandal M. Efficient magnetic localization and orientation technique for capsule endoscopy. In: Proceeding of IEEE/RSJ International Conference on Intelligent Robots and Systems, 2005
|
|
Viewed |
|
|
|
Full text
|
|
|
|
|
Abstract
|
|
|
|
|
Cited |
|
|
|
|
| |
Shared |
|
|
|
|
| |
Discussed |
|
|
|
|
