Synthesis and characterization of novel triblock
copolymers comprising poly(tetrahydrofuran) as a central block and
poly(-benzyl -glutamate)s as outer blocks

doi:10.1007/s11706-008-0015-7

2008, Vol. 2

Issue (1) : 84-90 https://doi.org/10.1007/s11706-008-0015-7

Synthesis and characterization of novel triblock copolymers comprising poly(tetrahydrofuran) as a central block and poly(-benzyl -glutamate)s as outer blocks

LI Hai-bin, TIAN Zhen, WANG Meng, ZHANG Ai-ying, FENG Zeng-guo

School of Materials Science and Engineering, Beijing Institute of Technology;

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Abstract BACKGROUND: Bioactive and biodegradable polyurethanes (BDPUs) have drawn much attention in recent years. As part of the research program to search for novel prepolymers for BDPUs, a study was carried out on the synthesis and characterization of triblock copolymers comprising poly(tetrahydrofuran) as a central block and poly(?-benzyl L-glutamate)s as outer blocks. RESULTS: A new macroinitiator terminated with phenylalanine was first prepared from the condensation of a distal hydroxy poly(tetrahydrofuran) with N-tert-butoxycarbonyl L-phenylalanine in the presence of dicyclohexylcarbodiimide, followed by removing the protecting group. Then, it was employed to initiate the ring-opening polymerization of ?-benzyl L-glutamate N-carboxyanhydride in varying feeding ratios to give rise to the targeted triblock copolymers. CONCLUSIONS: The length of the outer poly(?-benzyl L-glutamate) blocks was well tailored by varying the monomers to macroinitiator feeding ratio. All the triblock copolymers exhibited a nearly symmetrical and unimodal molecular weight distribution while only one distinct glass transition temperature was evidenced from -10°C to 25°C.

Issue Date: 05 March 2008

Cite this article:

TIAN Zhen,LI Hai-bin,WANG Meng, et al. Synthesis and characterization of novel triblock copolymers comprising poly(tetrahydrofuran) as a central block and poly(-benzyl -glutamate)s as outer blocks[J]. Front. Mater. Sci., 2008, 2(1): 84-90.

URL:

https://academic.hep.com.cn/foms/EN/10.1007/s11706-008-0015-7
https://academic.hep.com.cn/foms/EN/Y2008/V2/I1/84

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