摘要:探讨宫颈促成熟球囊用于足月妊娠促宫颈成熟的安全性及有效性。方法 选择西安交通大学医学院第一附属医院2011年2~10月有计划分娩指征的足月妊娠初产妇90例，随机分为两组，45例用宫颈促成熟球囊计划分娩为研究组，45例应用普贝生计划分娩促宫颈成熟为对照组。对两组促宫颈成熟情况及计划分娩效果、应用后至临产时间、分娩方式、分娩结局以及不良反应进行比较分析。结果 研究组放置球囊12小时后自然临产率为57.78％，明显高于对照组34.07％(χ2=6.02，p<0.05);研究组宫颈成熟率为100.00％，显著高于对照组79.02％(χ2=32.72，p <0.05);阴道分娩成功率明显高于对照组(χ2=6.11，p <0.05);研究组无母儿不良结局，对照组6例发生强制宫缩，4例发生胎儿窘迫，两组母儿不良结局有显著性差异，剖宫产率明显低于对照组(χ2=6.04，p <0.05)。结论 宫颈促成熟球囊计划分娩效果明显优于普贝生，无不良副作用，值得临床推广。To investigate safety and effectiveness of double-balloon device of promoting cervical ripening in planned delivery.Methods 90 primiparae who had indications of planned delivery in the First Affiliated Hospital of Medical College,Xi’an Jiaotong University from February to October,2011 were randomly divided into two group:study group(n=45,who were placed adouble-balloon device of cervical ripening) and control group(n=45,who were given PropessTM through vaginal).Cervical ripening situation,effect of planned delivery,time ftrom placement of the double-balloon device to onset of labor,pattern of delivery,delivery outcome and adverse reactions in the two groups were compared.Results 26 parturient women in the study group delivered naturally within 12 hours after using the double-balloon device with effective rate of 57.78% and 12 parturient women in the control group did so with effective rate of 34.07%.The effeetive rate in the study group was significantly higher than that in the control group(χ2=6.02,p<0.05). rhe cervical ripening rate in the study group was 100%,which was significantly higher than 79.02% in the control group (χ2=32.72,p<0.05).The successful rate of vaginal delivery in the study group was significantly higher than that in the control group (χ2=6.11,p<0.05).There were no maternal and neonatal adverse outcomes in study group, 6 cases with forced contractions and 4 cases with fetal distress were in control group. There were significantly differences between the two groups in maternal and neonatal outcomes, cesarean section rate in the study group was significantly lower than the control group(χ2=6.04,p<0.05).Conclusion In promoting ripening of the cervix,double-balloon device is significantly better than PropessTM through vaginal.So the application of double-balloon device of cervical ripening should be popularized in clinic.
