Please wait a minute...
Protein & Cell

ISSN 1674-800X

ISSN 1674-8018(Online)

CN 11-5886/Q

Postal Subscription Code 80-984

2018 Impact Factor: 7.575

Protein Cell    2016, Vol. 7 Issue (11) : 839-843    https://doi.org/10.1007/s13238-016-0325-y
LETTER
3-Anhydro-6-hydroxy-ophiobolin A displays high in vitro and in vivo efficacy against influenza A virus infection
Song Wang1,Xiaoqin Luo1,Ruoxiang Yan1,Quanxin Wang2,Qiuyue Qi2,Xiaojuan Chi1,Lanlan Zhang1,Ziding Yu1,Binxiang Cai1,Ji-Long Chen1,2(),Hongwei Liu2()
1. College of Animal Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China
2. Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China
 Download: PDF(570 KB)  
 Export: BibTeX | EndNote | Reference Manager | ProCite | RefWorks
Corresponding Author(s): Ji-Long Chen,Hongwei Liu   
Issue Date: 28 November 2016
 Cite this article:   
Song Wang,Xiaoqin Luo,Ruoxiang Yan, et al. 3-Anhydro-6-hydroxy-ophiobolin A displays high in vitro and in vivo efficacy against influenza A virus infection[J]. Protein Cell, 2016, 7(11): 839-843.
 URL:  
https://academic.hep.com.cn/pac/EN/10.1007/s13238-016-0325-y
https://academic.hep.com.cn/pac/EN/Y2016/V7/I11/839
1 Au TK, Chick WS, Leung PC (2000) The biology of ophiobolins. Life Sci 67:733–742
https://doi.org/10.1016/S0024-3205(00)00668-8
2 Cheng PK, Leung TW, Ho EC, Leung PC, Ng AY, Lai MY, Lim WW (2009) Oseltamivir-and amantadine-resistant influenza viruses A (H1N1). Emerg Infect Dis 15:966
https://doi.org/10.3201/eid1506.081357
3 Denisova OV, Kakkola L, Feng L, Stenman J, Nagaraj A, Lampe J, Yadav B, Aittokallio T, Kaukinen P, Ahola T (2012) Obatoclax, saliphenylhalamide, and gemcitabine inhibit influenza a virus infection. J Biol Chem 287:35324–35332
https://doi.org/10.1074/jbc.M112.392142
4 Droebner K, Pleschka S, Ludwig S, Planz O (2011) Antiviral activity of the MEK-inhibitor U0126 against pandemic H1N1v and highly pathogenic avian influenza virus in vitro and in vivo. Antiviral Res 92:195–203
https://doi.org/10.1016/j.antiviral.2011.08.002
5 Gao R, Cao B, Hu Y, Feng Z, Wang D, Hu W, Chen J, Jie Z, Qiu H, Xu K (2013) Human infection with a novel avian-origin influenza A (H7N9) virus. N Engl J Med 368:1888–1897
https://doi.org/10.1056/NEJMoa1304459
6 Haasbach E, Reiling SJ, Ehrhardt C, Droebner K, Ruckle A, Hrincius ER, Leban J, Strobl S, Vitt D, Ludwig S (2013) The NFkappaB inhibitor SC75741 protects mice against highly pathogenic avian influenza A virus. Antiviral Res 99:336–344
https://doi.org/10.1016/j.antiviral.2013.06.008
7 Hurt AC, Holien JK, Parker M, Kelso A, Barr IG (2009) Zanamivirresistant influenza viruses with a novel neuraminidase mutation. J Virol 83:10366–10373
https://doi.org/10.1128/JVI.01200-09
8 Karlas A, Machuy N, Shin Y, Pleissner KP, Artarini A, Heuer D, Becker D, Khalil H, Ogilvie LA, Hess S (2010) Genome-wide RNAi screen identifies human host factors crucial for influenza virus replication. Nature. 463:818–822
https://doi.org/10.1038/nature08760
9 Moscona A (2009) Global transmission of oseltamivir-resistant influenza. N Engl J Med 360:953–956
https://doi.org/10.1056/NEJMp0900648
10 Phuwapraisirisan P, Sawang K, Siripong P, Tip-Pyang S (2007) Anhydrocochlioquinone A, a new antitumor compound from Bipolaris oryzae. Tetrahedron Lett. 48:5193–5195
https://doi.org/10.1016/j.tetlet.2007.05.151
11 Planz O (2013) Development of cellular signaling pathway inhibitors as new antivirals against influenza. Antiviral Res 98:457–468
https://doi.org/10.1016/j.antiviral.2013.04.008
12 Regoes RR, Bonhoeffer S (2006) Emergence of drug-resistant influenza virus: population dynamical considerations. Science 312:389–391
https://doi.org/10.1126/science.1122947
13 Wang QX, Yang JL, Qi QY, Bao L, Yang XL, Liu MM, Huang P, Zhang LX, Chen JL, Cai L (2013) 3-Anhydro-6-hydroxyophiobolin A, a new sesterterpene inhibiting the growth of methicillin-resistant Staphylococcus aureus and inducing the cell death by apoptosis on K562, from the phytopathogenic fungus Bipolaris oryzae. Bioorg Med Chem Lett 23:3547–3550
https://doi.org/10.1016/j.bmcl.2013.04.034
14 Watanabe T, Watanabe S, Kawaoka Y (2010) Cellular networks involved in the influenza virus life cycle. Cell Host Microbe 7:427–439
https://doi.org/10.1016/j.chom.2010.05.008
15 Yang T, Lu Z, Meng L, Wei S, Hong K, Zhu W, Huang C (2012) The novel agent ophiobolin O induces apoptosis and cell cycle arrest of MCF-7 cells through activation of MAPK signaling pathways. Bioorg Med Chem Lett 22:579–585
https://doi.org/10.1016/j.bmcl.2011.10.079
[1] PAC-0839-16133-LHW_suppl_1 Download
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed