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Protein & Cell

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ISSN 1674-8018(Online)

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Protein Cell    2017, Vol. 8 Issue (11) : 796-800    https://doi.org/10.1007/s13238-017-0467-6
MINI-REVIEW
The lipid droplet: A conserved cellular organelle
Congyan Zhang1,2, Pingsheng Liu1,2()
1. National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China
2. University of Chinese Academy of Sciences, Beijing 100049, China
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Abstract

The lipid droplet (LD) is a unique multi-functional organelle that contains a neutral lipid core covered with a phospholipid monolayer membrane. The LDs have been found in almost all organisms from bacteria to humans with similar shape. Several conserved functions of LDs have been revealed by recent studies, including lipid metabolism and trafficking, as well as nucleic acid binding and protection. We summarized these findings and proposed a hypothesis that the LD is a conserved organelle.
Keywords lipid droplet      conserved organelle      lipid metabolism      nucleic acid handling     
Corresponding Author(s): Pingsheng Liu   
Issue Date: 30 November 2017
 Cite this article:   
Congyan Zhang,Pingsheng Liu. The lipid droplet: A conserved cellular organelle[J]. Protein Cell, 2017, 8(11): 796-800.
 URL:  
https://academic.hep.com.cn/pac/EN/10.1007/s13238-017-0467-6
https://academic.hep.com.cn/pac/EN/Y2017/V8/I11/796
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