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Effective and precise adenine base editing in mouse zygotes |
Puping Liang1,2( ), Hongwei Sun1, Xiya Zhang1, Xiaowei Xie1, Jinran Zhang1, Yaofu Bai1, Xueling Ouyang1, Shengyao Zhi1, Yuanyan Xiong1, Wenbin Ma1, Dan Liu4, Junjiu Huang1,2,3(), Zhou Songyang1,2,3,4() |
1. Key Laboratory of Gene Engineering of the Ministry of Education, Guangzhou Key Laboratory of Healthy Aging Research and SYSU-BCM Joint Research Center, School of Life Sciences, Sun Yat-sen University, Guangzhou 510275, China
2. Key Laboratory of Reproductive Medicine of Guangdong Province, School of Life Sciences and the First Affiliated Hospital, Sun Yatsen University, Guangzhou 510275, China
3. State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China
4. Verna and Marrs Mclean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA |
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Corresponding Author(s):
Puping Liang,Junjiu Huang,Zhou Songyang
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Issue Date: 21 September 2018
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Liang P, Ding C, Sun H, Xie X, Xu Y, Zhang X, Sun Y, Xiong Y, Ma W, Liu Yet al. (2017c) Correction of beta-thalassemia mutant by base editor in human embryos. Protein Cell 8:811–822
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