A novel intramolecular charge transfer fluorescent
chemosensor highly selective for Cu 2+ in
neutral aqueous solutions

doi:10.1007/s11458-010-0114-8

Front. Chem. China

2010, Vol. 5

Issue (2) : 178-183 https://doi.org/10.1007/s11458-010-0114-8

Research articles

A novel intramolecular charge transfer fluorescent chemosensor highly selective for Cu 2+ in neutral aqueous solutions

Qingxian LIAO¹,Aifang LI²,Zhao LI²,Yibin RUAN²,Yunbao JIANG²,

1.Department of Chemistry, College of Chemistry and Chemical Engineering, and Key Laboratory of Analytical Sciences, Xiamen University, Xiamen 361005, China；Xiamen Water Group Co. Ltd., Xiamen 361008, China; 2.Department of Chemistry, College of Chemistry and Chemical Engineering, and Key Laboratory of Analytical Sciences, Xiamen University, Xiamen 361005, China;

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Abstract A selective and sensitive intramolecular charge transfer (ICT) fluorescent chemosensor was designed for Cu²⁺ in neutral aqueous solutions of pH 7.0. The design of this totally water-soluble fluorescent chemosensor was based on the binding motif of Cu²⁺ to aminoacid, which is coupled to an ICT fluorophore bearing a 1,3,4-thiodiazole moiety in the electron acceptor. The formation of a 1:1 complex of Cu²⁺ to 2 was suggested to lead to fluorescence quenching. The quenching obeyed Stern-Volmer theory in neutral aqueous solution of pH 7.0 for Cu²⁺ over 5.0 × 10^−7 to 3.0 × 10^−5 mol·L^−1, with a quenching constant of 1.8 × 10⁵ L·mol^−1 and a detection limit of 2.0 × 10^−7 mol·L^−1. The binding of Cu²⁺ to 2 can be fully reversed by addition of chelator EDTA, affording a reversible sensing performance.

Keywords fluorescent chemosensor Cu2+ fluorescence quenching intramolecular charge transfer 4-thiodiazole

Issue Date: 05 June 2010

Cite this article:

Yunbao JIANG,Qingxian LIAO,Zhao LI, et al. A novel intramolecular charge transfer fluorescent chemosensor highly selective for Cu 2+ in neutral aqueous solutions[J]. Front. Chem. China, 2010, 5(2): 178-183.

URL:

https://academic.hep.com.cn/fcc/EN/10.1007/s11458-010-0114-8
https://academic.hep.com.cn/fcc/EN/Y2010/V5/I2/178

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