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Research and developments of laser assisted methods for translation into clinical application |
Ronald SROKA1,2(), Nikolas DOMINIK1,2, Max EISEL1,2, Anna ESIPOVA3, Christian FREYMÜLLER1,2, Christian HECKL1,2, Georg HENNIG1,2, Christian HOMANN1,2, Nicolas HOEHNE1,2, Robert KAMMERER2,5, Thomas KELLERER1,2, Alexander LANG1,2, Niklas MARKWARDT1,2, Heike POHLA2,4, Thomas PONGRATZ1,2, Claus-Georg SCHMEDT1,3, Herbert STEPP1,2, Stephan STRÖBL1,2, Keerthanan ULAGANATHAN1,2, Wolfgang ZIMMERMANN2,4, Adrian RUEHM1,2 |
1. Laser-Forschungslabor, LIFE-Center, Hospital of University, Ludwig-Maximilians University Munich, Munich, Germany 2. Department of Urology, Hospital of University, Ludwig-Maximilians University Munich, Munich, Germany 3. Department of Vascular Surgery, Diakonie Klinikum, Schwäbisch Hall, Germany 4. Labor für Tumorimmunologie, LIFE-Center, Hospital of University, Ludwig-Maximilians University Munich, Munich, Germany 5. Friedrich-Loeffler-Institute, Federal Research Institute for Animal Health, Greifswald- Insel Riems, Germany |
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Abstract Biophotonics and laser medicine are very dynamic and continuously increasing fields ecologically as well as economically. Direct communication with medical doctors is necessary to identify specific requests and unmet needs. Information on innovative, new or renewed techniques is necessary to design medical devices for introduction into clinical application and finally to become established after positive clinical trials as well as medical approval. The long-term endurance in developing light based innovative clinical concepts and devices are described based on the Munich experience. Fluorescence technologies for laboratory medicine to improve non-invasive diagnosis or for online monitoring are described according with new approaches in improving photodynamic therapeutic aspects related to immunology. Regarding clinically related thermal laser applications, the introduction of new laser wavelengths and laser parameters showed potential in the treatment of varicose veins as well as in lithotripsy. Such directly linked research and development are possible when researchers and medical doctors perform their daily work in immediate vicinity, thus have the possibility to share their ideas in meetings by day.
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Keywords
translational biophotonics
thermal laser application
fluorescence diagnosis
on-line monitoring
lithotripsy
phlebology
photodynamic therapy (PDT)
laboratory medicine
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Corresponding Author(s):
Ronald SROKA
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Just Accepted Date: 04 July 2017
Online First Date: 29 August 2017
Issue Date: 26 September 2017
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