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Bipolar electrocoagulation on functional cortex (BCFC) for intractable epilepsy involving eloquent cortex: a review |
Xinghui He1,2, Guoming Luan1,2,3* |
1.Beijing Key Laboratory of Epilepsy, Sanbo Brain Hospital, Capital Medical University, Beijing 100093, China
2.Department of Neurosurgery, Epilepsy Center, Sanbo Brain Hospital, Capital Medical University, Beijing 100093, China
3.Institute of Epilepsy, Beijing Institute for Brain Disorders, Capital Medical University, Beijing 100069, China |
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Abstract Twenty percent to forty percent of patients with epilepsy are medically refractory. For these patients, epilepsy surgeries such as resecting the epileptogenic focus may provide an alternative option. However, when the epileptogenic focus is located in the eloquent cortex, the resection of epileptogenic focus may lead to unacceptable functional deficits. Bipolar electrocoagulation on functional cortex (BCFC) is a surgical technique that holds the same principles with multiple subpial transections (MST) and aims to benefit patients with epilepsy whose epileptogenic zone is located in the eloquent cortex. It uses thermal injury to interrupt the horizontal fibers in the cortex while mechanical injury is used in MST. Here, we reviewed the rationale, surgical procedure, laboratory research, and clinical application of BCFC. We also discussed the ongoing challenges of BCFC.
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Keywords
functional cortex
epilepsy surgery
bipolar electrocoagulation on functional cortex (BCFC)
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Issue Date: 01 September 2018
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