Research progress on BDNF in Sjögren’s syndrome with depressive disorder

doi:10.3868/j.issn.2096-0689.2022.03.003

Journal of Translational Neuroscience

2022, Vol. 7

Issue (3) : 15-19 https://doi.org/10.3868/j.issn.2096-0689.2022.03.003

Research progress on BDNF in Sjögren’s syndrome with depressive disorder

Yuhang Liang, Tiankai Jiang, Tiantian Jiang, Changqing Gao^*

Department of Clinical Psychology, The Affiliated Mental Hospital of Kunming Medical University, Kunming 650000, China

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Abstract Brain-derived neurotrophic factor (BDNF) is a widely studied neurotrophic factor, which plays an important role in the growth, development, differentiation, injury, repair, survival and apoptosis of nerve cells. More and more studies have found that there is a high prevalence of depressive disorders in patients with autoimmune diseases. Sjögren’s syndrome is a chronic autoimmune exocrine disease characterized by lymphocytic infiltration and exocrine gland destruction. Depressive disorders are common in patients with Sjögren’s syndrome. The quality of life of patients with Sjögren’s syndrome with depression was generally lower than that of patients with Sjögren’s syndrome without depression. In this article, we reviewed the research progress of BDNF and depression in Sjögren’s syndrome at home and abroad.

Keywords brain-derived neurotrophic factor (BDNF) sjögren’s syndrome depressive disorder

Issue Date: 25 September 2022

Cite this article:

Yuhang Liang, Tiankai Jiang, Tiantian Jiang, Changqing Gao. Research progress on BDNF in Sjögren’s syndrome with depressive disorder[J]. Journal of Translational Neuroscience,2022, 7(3): 15-19.

URL:

https://academic.hep.com.cn/jtn/EN/10.3868/j.issn.2096-0689.2022.03.003
https://academic.hep.com.cn/jtn/EN/Y2022/V7/I3/15

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