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Intracranial arterial stenosis in young adults: risk factors, diagnosis and treatment |
| Xiao Dong1, Yuanyuan Liu1, Lijing Tang2, Xuehong Chu1, Erlan Yu1, Xiaole Jia1, Chuanjie Wu1* |
1.Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China
2.Department of Neurology, Zhuolu County Hospital of Chinese Medicine, Zhangjiakou 075600, China |
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Abstract Intracranial artery stenosis (ICAS) in youth is an under-explored condition. ICAS is one of the leading causes of stroke in young people worldwide and confers a higher risk of stroke recurrence, leading to a poor prognosis for individuals and a great burden to society. The etiology and risk factors of ICAS in youth differ from those of older patients, thus resulting in a difference in the progression and prognosis of the disease. Even though the diagnosis of ICAS is lumen-based, it is sometimes difficult to identify in young patients based on imaging alone. Notably, novel vessel wall imaging techniques play an important role in determining the cause of stenosis and screening patients at high risk of recurrence. Moreover, pharmacologic regimens and risk factor control goals for ICAS in young adults are largely consistent with those in older patients. Thus, considering the poor prognosis, there is an urgent need for high-quality studies in the young ICAS population to analyze the high-quality observational data collected.
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| Keywords
intracranial artery stenosis
young stroke
intracranial atherosclerotic stenosis
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Issue Date: 25 March 2024
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