Best operating conditions to produce hydroxyapatite nanoparticles by means of a spinning disc reactor

doi:10.1007/s11705-014-1427-9

Front. Chem. Sci. Eng.

2014, Vol. 8

Issue (2) : 156-160 https://doi.org/10.1007/s11705-014-1427-9

RESEARCH ARTICLE

Best operating conditions to produce hydroxyapatite nanoparticles by means of a spinning disc reactor

A. F. D’ Intino,B. de Caprariis,M.L. Santarelli,N. Verdone,A. Chianese(

)

Department of Chemical Engineering, Sapienza University, via Eudossiana 00184 Rome, Italy

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Abstract

In this work, Mg²⁺ doped hydroxyapatite (Mg-HAP) nanoparticles were produced by a reaction-precipitation process by using a spinning disc reactor (SDR) at high rotational speed. The production process of these nanoparticles consisted of the neutralization reaction between two aqueous solutions of calcium chloride and ammonia orthophosphate at room temperature. By operating at pH= 10, a high purity Mg-HAP nanoparticles were obtained. In particular, they were 51 nm in average size when the two reagents were fed over the disc symmetrically at 3 cm from the disc center and a rotational speed of the disc reactor equal to 1400 r/min was adopted.

Keywords hydroxyapatite nanoparticles spinning disc reactor

Corresponding Author(s): A. Chianese

Issue Date: 22 May 2014

Cite this article:

A. F. D’ Intino,B. de Caprariis,M.L. Santarelli, et al. Best operating conditions to produce hydroxyapatite nanoparticles by means of a spinning disc reactor[J]. Front. Chem. Sci. Eng., 2014, 8(2): 156-160.

URL:

https://academic.hep.com.cn/fcse/EN/10.1007/s11705-014-1427-9
https://academic.hep.com.cn/fcse/EN/Y2014/V8/I2/156

Fig.1 Spinning disc reactor (SDR) design

Fig.2 Layout of the reagents feed locations at 2 cm and 3 cm

Fig.3 Average particle size of Mg-HAP particles produced at 1400 rpm as a function of each reagent solution flow rate

Fig.4 Mg-HAP particle average size vs rotational speed for 2 and 3 cm feed points

Fig.5 Influence of speed rotation on residence time and specific dispersed power

Fig.6 Black: XRD pattern of Mg-HAP, x = 0.1, Fadeev [20]; Red: XRD pattern of the Mg-HAP powder, x = 0.566, produced in this work at 1400 rpm, a feed point of 3 cm and a flow rate of 2 mL/s.

Fig.7 SEM image of Mg-HAP nanoparticles produced at 1400 rpm, a feed point of 3 cm and a flow rate of 2 mL/s

Fig.8 FT-IR spectra of the Mg-HAP and HAP particles produced at 1400 rpm, a feed point of 3 cm and a flow rate of 2 mL/s. Blue: produced Mg-HAP sample; Red: HAP reference sample, Silverstein?? et al. [21].

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