Comprehensive insight into the occurrence characteristics, influencing factors and risk assessments of antibiotics in the Chaohu Basin

doi:10.1007/s11783-024-1817-2

2024, Vol. 18

Issue (5) : 57 https://doi.org/10.1007/s11783-024-1817-2

Comprehensive insight into the occurrence characteristics, influencing factors and risk assessments of antibiotics in the Chaohu Basin

Shuanggang Hu¹, Hongzhi Zhang¹, Yongjie Yang¹, Kangping Cui¹, Junjie Ao², Xuneng Tong³(

), Mengchen Shi⁴, Yi Wang⁴, Xing Chen¹, Chenxuan Li¹, Yihan Chen¹(

)

¹. School of Resources and Environmental Engineering, Hefei University of Technology, Hefei 230009, China
². Ministry of Education-Shanghai Key Laboratory of Children’s Environmental Health, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China
³. Department of Civil & Environmental Engineering, National University of Singapore, Singapore 117576, Singapore
⁴. College of Resources and Environment, Anhui Agricultural University, Hefei 230036, China

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Abstract

● Clindamycin predominates in the waters, while tetracycline prevails in the sediments.

● Occurrence of antibiotics are significantly different between rivers and lakes.

● There is a strong association between nutrients and antibiotics.

● Sulfamethoxazole, tetracycline, and two lincosamides ranked top four highest risks.

The pollution of antibiotics in aquatic environments has received extensive attention. Yet, research on antibiotic contamination in river-lake systems, a significant form of modern aquatic environments, still needs to be explored. This study focuses on the Chaohu Basin (China) investigating the occurrence characteristics, influencing factors, and risk assessments of antibiotics in the river-lake system. The total antibiotic concentrations in the water phase and sediment phase were 3.14–1887.49 ng/L and 0.92–1553.75 ng/g, respectively. Clindamycin was the predominant antibiotic in the water phase, whereas tetracycline prevailed in the sediment phase. Notable differences in concentration and structural composition of antibiotics between the tributaries (river system) and Chaohu Lake were observed, indicating the involvement of various geochemical processes in the attenuation of antibiotics during transport to the receiving lake. Spatial analysis suggested that the western river is the primary source of antibiotics in Chaohu Lake. Controlling nutrient influx in heavily polluted areas is crucial to addressing the escalating issue of antibiotic pollution in the river-lake system. The widespread occurrence of clindamycin in the waters is likely due to wastewater treatment plant discharges, and high-intensity human activities continue to exacerbate antibiotic contamination. Risk assessment indicated that sulfamethoxazole, tetracycline, lincomycin, and clindamycin ranked in the top four with the highest risks to the most sensitive aquatic organisms. Nonetheless, the antibiotics presented no risk to consumer health. This study provides valuable insights for controlling antibiotic pollution in river-lake systems.

Keywords Antibiotics Occurrence characteristics Influencing factors Risk assessments River-lake system

Corresponding Author(s): Xuneng Tong,Yihan Chen

Issue Date: 24 January 2024

Cite this article:

Shuanggang Hu,Hongzhi Zhang,Yongjie Yang, et al. Comprehensive insight into the occurrence characteristics, influencing factors and risk assessments of antibiotics in the Chaohu Basin[J]. Front. Environ. Sci. Eng., 2024, 18(5): 57.

URL:

https://academic.hep.com.cn/fese/EN/10.1007/s11783-024-1817-2
https://academic.hep.com.cn/fese/EN/Y2024/V18/I5/57

Fig.1 Antibiotic concentrations in the waters (a) and sediments (b) of Chaohu Basin were shown using box plots.

Fig.2 Comparison of total antibiotic concentration ((a), (c), (e), respectively) and structural composition ((b), (d), (f), respectively). Significant effects on measurement variation were determined using the Wilcox test. Principal coordinate analysis (PCoA) based on Bray-Curtis distances revealed this difference in the structural composition of antibiotics.

Fig.3 RDA of the antibiotic concentrations and environmental factors in the waters ((a) river system; (b) lake system) and sediments ((c) river system; (d) lake system). Antibiotics with low detection (< 50.0%) were excluded.

Fig.4 Correlation analysis of antibiotic concentrations and DOM parameters in the waters ((a) river system; (b) lake system) and sediments ((c) river system; (d) lake system) of the Chaohu Basin. Antibiotics with low detection (< 50.0%) were excluded. *: P < 0.05; **: P < 0.01; ***: P < 0.001.

Fig.5 Risk quotients (RQs) and species sensitivity distribution (SSD) of selected antibiotics for aquatic organisms in the water phase. (a) risk quotients of selected antibiotics were derived using their average concentrations over most sensitive endpoints; (b) the most sensitive species for selected antibiotics were noted; (c) species sensitivity distribution (SSD) curves for seven major antibiotics with higher RQs; (d) parameter (HC₅) of SSD curves and PAF values for aquatic organisms under different antibiotic concentrations; (e) assessing risk levels based on analysis of SSD.

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