Environmental effects and risk control of antibiotic resistance genes in the organic solid waste aerobic composting system: A review

doi:10.1007/s11783-021-1415-5

Front. Environ. Sci. Eng.

2021, Vol. 15

Issue (6) : 127 https://doi.org/10.1007/s11783-021-1415-5

FEATURE ARTICLE

Environmental effects and risk control of antibiotic resistance genes in the organic solid waste aerobic composting system: A review

Caihong Huang^1,², Zhurui Tang^1,^2,³, Beidou Xi^1,^2,⁴(

), Wenbing Tan^1,², Wei Guo^1,², Weixia Wu^1,^2,⁵, Caiyun Ma^1,^2,⁴

¹. State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environmental Sciences, Beijing 100012, China
². Innovation Base of Ground Water & Environmental System Engineering, Chinese Research Academy of Environmental Sciences, Beijing 100012, China
³. State Key Laboratory of Urban Water Resource and Environment, School of Environment, Harbin Institute of Technology, Harbin 150090, China
⁴. School of Environmental and Municipal Engineering, Lanzhou Jiaotong University, Lanzhou 730070, China
⁵. College of Environmental Science and Engineering, Guilin University of Technology, Guilin 541004, China

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Abstract

• ARGs were detected in livestock manure, sludge, food waste and fermentation dregs.

• The succession of microbial community is an important factor affecting ARGs.

• Horizontal transfer mechanism of ARGs during composting should be further studied.

Antibiotic resistance genes (ARGs) have been diffusely detected in several kinds of organic solid waste, such as livestock manure, sludge, antibiotic fermentation residues, and food waste, thus attracting great attention. Aerobic composting, which is an effective, harmless treatment method for organic solid waste to promote recycling, has been identified to also aid in ARG reduction. However, the effect of composting in removing ARGs from organic solid waste has recently become controversial. Thus, this article summarizes and reviews the research on ARGs in relation to composting in the past 5 years. ARGs in organic solid waste could spread in different environmental media, including soil and the atmosphere, which could widen environmental risks. However, the conventional composting technology had limited effect on ARGs removal from organic solid waste. Improved composting processes, such as hyperthermophilic temperature composting, could effectively remove ARGs, and the HGT of ARGs and the microbial communities are identified as vital influencing factors. Currently, during the composting process, ARGs were mainly affected by three response pathways, (I) “Microenvironment-ARGs”; (II) “Microenvironment-microorganisms-ARGs”; (III) “Microorganisms-horizontal gene transfer-ARGs”, respectively. Response pathway II had been studied the most which was believed that microbial community was an important factor affecting ARGs. In response pathway III, mainly believed that MGEs played an important role and paid less attention to eARGs. Further research on the role and impact of eARGs in ARGs may be considered in the future. It aims to provide support for further research on environmental risk control of ARGs in organic solid waste.

Keywords Antibiotic resistance genes Organic solid waste Aerobic composting Livestock manure Sludge

Corresponding Author(s): Beidou Xi

Issue Date: 17 March 2021

Cite this article:

Caihong Huang,Zhurui Tang,Beidou Xi, et al. Environmental effects and risk control of antibiotic resistance genes in the organic solid waste aerobic composting system: A review[J]. Front. Environ. Sci. Eng., 2021, 15(6): 127.

URL:

https://academic.hep.com.cn/fese/EN/10.1007/s11783-021-1415-5
https://academic.hep.com.cn/fese/EN/Y2021/V15/I6/127

Fig.1 Transmission of antibiotics resistant bacteria and antibiotics resistant genes in organic solid waste across environmental media.

Fig.2 Three main ARGs response pathways in compost. ① “Microenvironment-ARGs”; ② “Microenvironment-microorganisms-ARGs”; ③ “Microorganisms-HGT-ARGs”.

Auxiliary materials	Raw materials	Scales	Additive amount	Composting period	Target ARGs/MGEs	Change type^a	Removal/ Increasing rate	Reference
Natural zeolite	Sludge	Laboratory	1% wet weight	183	bla_CTX-M,bla_TEM, ermB, ereA, tetW	D	0.3–2 logs	Zhang et al., 2016a
Natural zeolite	Sludge	Laboratory	1% wet weight	183	ermF, sul1, sul2, tetG, tetX, mefA, aac(6’)-Ib-cr)	I	0.3–1.3 logs	Zhang et al., 2016a
Zeolite	Chicken manure	Full	350 kg zeolite in 7t raw materials	31	total target ARGs	D	86.50%	Peng et al., 2018
Zeolite	Swine manure	Laboratory	5%	40	tetC,tetG,tetQ,tetX,tetM, aac, ermB	D	0.23–1.09 logs	Qian et al., 2019
Biochar	Swine manure	Laboratory	10%	40		D
Fly ash	Swine manure	Laboratory	5%	40		D
Biochars	Chicken manure	Laboratory	5%	42	total target ARGs	D	0.86 log	Cui et al., 2016
Mushroom residues	Chicken manure	Laboratory	10% (w/w)	–	intl1, sul	D	–	Zhang et al., 2019a
	Chicken manure	Laboratory	10% (w/w)	–	qnr	I	–
	Swine manure	Laboratory	10% (w/w)	–	sul	D	–
	Swine manure	Laboratory	10% (w/w)	–	tet, erm, qnr	I	–
Rice husk	Chicken manure	Laboratory	10% (w/w)	–	sul, erm and qnr	D	–
Rice husk	Swine manure	Laboratory	10% (w/w)	–	qnr	D	–
Sawdust	Chicken manure	Laboratory	10% (w/w)	–	intl1, sul, erm and qnr	D	–
Sawdust	Swine manure	Laboratory	10% (w/w)	–	intl1, sul, tet	D	–
Nano-zerovalent iron	Swine manure	Laboratory	100 mg/kg	30	sul1, sul2, dfrA7, ermF, ermX, intI2, Tn916/1545	D	33.26%–99.31%	Wang et al., 2020b
Surfactants	Chicken manure	Laboratory	0.15%	26	13 ARGs	D	–	Zhang et al., 2016b
Chinese medicinal herbal residues	Swine manure	Laboratory	41.67% dry weight basis	40	most of the targeted ARGs	D	0.18–2.82 logs	Zhang et al., 2017a
Superphosphate	Chicken manure	Full	350 kg calcium superphosphate in 7t raw materials	31	total target ARGs	D	68.60%	Peng et al., 2018
Zeolite and ferrous sulfate	Chicken manure	Full	350 kg zeolite and 210 kg ferrous sulfate in 7t raw materials	31	total target ARGs	D	72.20%	Peng et al., 2018
Coal gasification slag	Swine manure	Laboratory	5% and 10% CGS	30	5/11 ARGs	D	–	Lu et al., 2018
Ferric chloride	Chicken manure	Laboratory	5%	44	total ARGs	D	21.41%–73.24%	Guo et al., 2020
Superabsorbent polymers	Swine manure	Laboratory	5 and 15 mg/kg	35	tetW,dfrA7,ermX,aac(6')-ib-cr	D	>90%	Guo et al., 2017
Macroporous adsorption resin	Swine manure	Laboratory	5% and 15%	30	Total target ARGs	D	14.14%–99.44%	Bao et al., 2020
Bamboo charcoal and bamboo vinegar	Swine manure	Laboratory	3% bamboo charcoal+ 0.4% bamboo vinegar	42	Total ARGs	D	94.75%–98.40%	Guo et al., 2019b

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