Organ function support in patients with coronavirus disease 2019: Tongji experience

doi:10.1007/s11684-020-0774-9

Front. Med.

2020, Vol. 14

Issue (2) : 232-248 https://doi.org/10.1007/s11684-020-0774-9

CONSENSUS

Organ function support in patients with coronavirus disease 2019: Tongji experience

Yong Li¹, Fan He², Ning Zhou^3,⁴, Jia Wei⁵, Zeyang Ding^6,⁷, Luyun Wang^3,⁴, Peng Chen^3,⁴, Shuiming Guo², Binhao Zhang^6,⁷, Xiaoning Wan^3,⁴, Wei Zhu⁸(

), on behalf of Multidisciplinary Team for COVID-19, Optical Valley Branch of Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China¹

¹. Department of Respiratory and Critical Care Medicine, Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
². Department of Nephrology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
³. Department of Cardiology, Department of Internal Medicine and Genetic Diagnosis Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
⁴. Hubei Key Laboratory of Genetics and Molecular Mechanism of Cardiological Disorders, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
⁵. Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
⁶. Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
⁷. Hubei Key Laboratory of HPB Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
⁸. Department of Emergency and Critical Care Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China

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Abstract

Coronavirus disease 2019 (COVID-19) is a highly contagious disease and a serious threat to human health. COVID-19 can cause multiple organ dysfunction, such as respiratory and circulatory failure, liver and kidney injury, disseminated intravascular coagulation, and thromboembolism, and even death. The World Health Organization reports that the mortality rate of severe-type COVID-19 is over 50%. Currently, the number of severe cases worldwide has increased rapidly, but the experience in the treatment of infected patients is still limited. Given the lack of specific antiviral drugs, multi-organ function support treatment is important for patients with COVID-19. To improve the cure rate and reduce the mortality of patients with severe- and critical-type COVID-19, this paper summarizes the experience of organ function support in patients with severe- and critical-type COVID-19 in Optical Valley Branch of Tongji Hospital, Wuhan, China. This paper systematically summarizes the procedures of functional support therapies for multiple organs and systems, including respiratory, circulatory, renal, hepatic, and hematological systems, among patients with severe- and critical-type COVID-19. This paper provides a clinical reference and a new strategy for the optimal treatment of COVID-19 worldwide.

Keywords COVID-19 severe and critical type organ function support

Corresponding Author(s): Wei Zhu

Just Accepted Date: 02 April 2020 Online First Date: 27 April 2020 Issue Date: 09 May 2020

Cite this article:

Yong Li,Fan He,Ning Zhou, et al. Organ function support in patients with coronavirus disease 2019: Tongji experience[J]. Front. Med., 2020, 14(2): 232-248.

URL:

https://academic.hep.com.cn/fmd/EN/10.1007/s11684-020-0774-9
https://academic.hep.com.cn/fmd/EN/Y2020/V14/I2/232

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