A review on anammox process for the treatment of antibiotic-containing wastewater: Linking effects with corresponding mechanisms

doi:10.1007/s11783-020-1309-y

Front. Environ. Sci. Eng.

2021, Vol. 15

Issue (1) : 17 https://doi.org/10.1007/s11783-020-1309-y

REVIEW ARTICLE

A review on anammox process for the treatment of antibiotic-containing wastewater: Linking effects with corresponding mechanisms

Jinjin Fu, Quan Zhang, Baocheng Huang, Niansi Fan(

), Rencun Jin(

)

Laboratory of Water Pollution Remediation, School of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, China

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Abstract

• Anammox is promising for nitrogen removal from antibiotic-containing wastewater.

• Most antibiotics could inhibit the anammox performance and activity.

• Antibiotic pressure promoted the increase in antibiotic resistance genes (ARGs).

• Antibiotic-resistance mechanisms of anammox bacteria are speculated.

Antibiotic is widely present in the effluent from livestock husbandry and the pharmaceutical industry. Antibiotics in wastewater usually have high biological toxicity and even promote the occurrence and transmission of antibiotic resistant bacteria and antibiotic resistance genes. Moreover, most antibiotic-containing wastewater contains high concentration of ammonia nitrogen. Improper treatment will lead to high risk to the surrounding environment and even human health. The anaerobic ammonium oxidation (anammox) with great economic benefit and good treatment effect is a promising process to remove nitrogen from antibiotic-containing wastewater. However, antibiotic inhibition has been observed in anammox applications. Therefore, a comprehensive overview of the single and combined effects of various antibiotics on the anammox system is conducted in this review with a focus on nitrogen removal performance, sludge properties, microbial community, antibiotic resistance genes and anammox-involved functional genes. Additionally, the influencing mechanism of antibiotics on anammox consortia is summarized. Remaining problems and future research needs are also proposed based on the presented summary. This review provides a better understanding of the influences of antibiotics on anammox and offers a direction to remove nitrogen from antibiotic-containing wastewater by the anammox process.

Keywords Anammox Antibiotic Mechanism Inhibition

Corresponding Author(s): Niansi Fan,Rencun Jin

Issue Date: 26 August 2020

Cite this article:

Jinjin Fu,Quan Zhang,Baocheng Huang, et al. A review on anammox process for the treatment of antibiotic-containing wastewater: Linking effects with corresponding mechanisms[J]. Front. Environ. Sci. Eng., 2021, 15(1): 17.

URL:

https://academic.hep.com.cn/fese/EN/10.1007/s11783-020-1309-y
https://academic.hep.com.cn/fese/EN/Y2021/V15/I1/17

Tab.1 The effects of antibiotics on the performance of the anammox process.

Tab.2 Summary of the specific anammox activity in the presence of antibiotics

Tab.3 The dynamic variations of different AnAOB in anammox systems under antibiotics pressure.

Fig.1 Possible tolerance mechanism of AnAOB to OTC and SMX, adapted from (^{Zhang et al., 2019b}) with permission.

Fig.2 Co-selection mechanism of antibiotic and metal resistant: (a) co-resistance mechanism; (b) cross-resistance mechanism; (c) co-regulation mechanism. Circles, triangles, and rectangles represent antibiotics, heavy metals and efflux pumps, respectively. Different colors show different substances mentioned above.

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