Human gut microbiota: the links with dementia development

doi:10.1007/s13238-016-0338-6

Protein Cell

2017, Vol. 8

Issue (2) : 90-102 https://doi.org/10.1007/s13238-016-0338-6

REVIEW

Human gut microbiota: the links with dementia development

Rashad Alkasir¹,Jing Li¹,Xudong Li²,Miao Jin²,Baoli Zhu^1,³(

)

¹. Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China
². China-Japan Friendship Hospital, Beijing 100029, China
³. Collaborative Innovation Centre for Diagnosis and Treatment of Infectious Diseases, The First Attainted Hospital College of Medicine, Zhejiang University, Hangzhou 310058, China

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Abstract

Dementia is a comprehensive category of brain diseases that is great enough to affect a person’s daily functioning. The most common type of dementia is Alzheimer’s disease, which makes most of cases. New researches indicate that gastrointestinal tract microbiota are directly linked to dementia pathogenesis through triggering metabolic diseases and low-grade inflammation progress. A novel strategy is proposed for the management of these disorders and as an adjuvant for psychiatric treatment of dementia and other related diseases through modulation of the microbiota (e.g. with the use of probiotics).

Keywords dementia alzheimer’s disease gut microbiota inflammation probiotics

Corresponding Author(s): Baoli Zhu

Issue Date: 17 March 2017

Cite this article:

Rashad Alkasir,Jing Li,Xudong Li, et al. Human gut microbiota: the links with dementia development[J]. Protein Cell, 2017, 8(2): 90-102.

URL:

https://academic.hep.com.cn/pac/EN/10.1007/s13238-016-0338-6
https://academic.hep.com.cn/pac/EN/Y2017/V8/I2/90

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