Recent advances in pharmaceuticals and personal care products in the surface water and sediments in China

doi:10.1007/s11783-016-0868-4

Front. Environ. Sci. Eng.

0, Vol.

Issue () : 2 https://doi.org/10.1007/s11783-016-0868-4

REVIEW ARTICLE

Recent advances in pharmaceuticals and personal care products in the surface water and sediments in China

Wentao Zhao^1,³(

),Ying Guo²,Shuguang Lu²,Pingping Yan²,Qian Sui^2,³(

)

¹. State Key Laboratory of Pollution Control and Resource Reuse, College of Environmental Science and Engineering, Tongji University, Shanghai 200092, China
². State Environmental Protection Key Laboratory of Environmental Risk Assessment and Control on Chemical Process, School of Resources and Environmental Engineering, East China University of Science and Technology, Shanghai 200237, China
³. Beijing Key Laboratory for Emerging Organic Contaminants Control, Tsinghua University, Beijing 100084, China

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Abstract

Recent publications on PPCPs in surface water environment in China were reviewed.

Antibiotics received more attention than other PPCPs in surface water environment.

Uneven attention has been focused across different study areas in China.

Sulfamethoxazole showed the most significant environmental risk in surface water.

Higher risks were posed by PPCPs in sediments than in surface water.

Pharmaceuticals and personal care products (PPCPs) have been regarded as an emerging problem in the surface water environment in the past few decades. In China, although related studies were initiated several years ago, an increasing number of studies on this topic have been conducted in recent years. These studies have expanded knowledge of their occurrence, behavior and associated risk in the surface water environment in China. This review compiles the most recent literature related to the studies of PPCPs in the surface water environment in China. It includes PPCP occurrence in surface water and sediments, their geographical distribution, and outcomes of the associated risk assessment. It shows that antibiotics have received much more attention in both surface water and sediments than other PPCPs. Compared to other countries; most antibiotics in the collected sediments in China showed higher contamination levels. Many more study areas have been covered in recent years; however, attention has been given to only specific areas. Environmental risk assessment based on risk quotients indicated that sulfamethoxazole presents the most significant environmental risk to relevant aquatic organisms; followed by ofloxacin, ciprofloxacin, enrofloxacin, 17α-ethynylestradiol, ibuprofen and diclofenac. Despite limited research on the environmental risk assessment of PPCPs in sediments, higher risks posed by PPCPs in the sediments rather than surface water were identified highlighting the need for further risk assessment of PPCPs in sediment samples.

Keywords Surface water Sediment Antibiotics Geographical distribution Risk assessment

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Corresponding Author(s): Wentao Zhao,Qian Sui

Issue Date: 20 September 2016

Cite this article:

Wentao Zhao,Ying Guo,Shuguang Lu, et al. Recent advances in pharmaceuticals and personal care products in the surface water and sediments in China[J]. Front. Environ. Sci. Eng., 0, (): 2.

URL:

https://academic.hep.com.cn/fese/EN/10.1007/s11783-016-0868-4
https://academic.hep.com.cn/fese/EN/Y0/V/I/2

Fig.1 Number of times that PPCPs was reported in the surface water of China in research papers published during 2012–2015 (only PPCPs which were reported more than five times are shown)

Fig.2 Statistical analysis of average concentrations of most reported PPCPs in the surface water of China in research papers published during 2012–2015

Fig.3 Number of times that PPCPs was reported in the sediments of China during 2012–2015 (only PPCPs which were reported more than five times are shown)

Fig.4 Statistical analysis of average concentrations of most reported PPCPs in the sediments of China in research papers published during 2012–2015

Fig.5 PPCPs reported in the surface water environment ((a) surface water; (b) sediments) from different provinces during 2012–2015

1	Daughton C G, Ternes T A. Pharmaceuticals and personal care products in the environment: agents of subtle change? Environmental Health Perspectives, 1999, 107(Suppl 6): 907–938 https://doi.org/10.1289/ehp.99107s6907 pmid: 10592150
2	Corbel V, Stankiewicz M, Pennetier C, Fournier D, Stojan J, Girard E, Dimitrov M, Molgó J, Hougard J M, Lapied B. Evidence for inhibition of cholinesterases in insect and mammalian nervous systems by the insect repellent deet. BMC Biology, 2009, 7(1): 47 https://doi.org/10.1186/1741-7007-7-47 pmid: 19656357
3	Ricart M, Guasch H, Alberch M, Barceló D, Bonnineau C, Geiszinger A, Farré M, Ferrer J, Ricciardi F, Romaní A M, Morin S, Proia L, Sala L, Sureda D, Sabater S. Triclosan persistence through wastewater treatment plants and its potential toxic effects on river biofilms. Aquatic Toxicology (Amsterdam, Netherlands), 2010, 100(4): 346–353 https://doi.org/10.1016/j.aquatox.2010.08.010 pmid: 20855117
4	European Commission. Directive 2000/60/EC of the European Parliament and of the Council establishing a framework for the Community action in the field of water policy, 23 October 2000. Official Journal of the European Communities, 2000, 12: L327
5	Barbosa M O, Moreira N F F, Ribeiro A R, Pereira M F R, Silva A M T. Occurrence and removal of organic micropollutants: An overview of the watch list of EU Decision 2015/495. Water Research, 2016, 94: 257–279 https://doi.org/10.1016/j.watres.2016.02.047 pmid: 26967909
6	Schwab B W, Hayes E P, Fiori J M, Mastrocco F J, Roden N M, Cragin D, Meyerhoff R D, D’Aco V J, Anderson P D. Human pharmaceuticals in US surface waters: a human health risk assessment. Regulatory Toxicology and Pharmacology, 2005, 42(3): 296–312 https://doi.org/10.1016/j.yrtph.2005.05.005 pmid: 15979221
7	Kümmerer K. Antibiotics in the aquatic environment: a review—Part I. Chemosphere, 2009, 75(4): 417–434 https://doi.org/10.1016/j.chemosphere.2008.11.086 pmid: 19185900
8	Mompelat S, Le Bot B, Thomas O. Occurrence and fate of pharmaceutical products and by-products, from resource to drinking water. Environment International, 2009, 35(5): 803–814 https://doi.org/10.1016/j.envint.2008.10.008 pmid: 19101037
9	Liu J L, Wong M H. Pharmaceuticals and personal care products (PPCPs): a review on environmental contamination in China. Environment International, 2013, 59(3): 208–224 https://doi.org/10.1016/j.envint.2013.06.012 pmid: 23838081
10	Bu Q, Wang B, Huang J, Deng S, Yu G. Pharmaceuticals and personal care products in the aquatic environment in China: a review. Journal of Hazardous Materials, 2013, 262(22): 189–211 https://doi.org/10.1016/j.jhazmat.2013.08.040 pmid: 24036145
11	Yang G, Fan M, Zhang G. Emerging contaminants in surface waters in China: a short review. Environmental Research Letters, 2014, 9(7): 1–13 https://doi.org/10.1088/1748-9326/9/7/074018
12	Yin L N, Wang B, Ma R X, Yuan H L, Yu G. Enantioselective environmental behavior and effect of chiral PPCPs. Progress in Chemistry., 2016, 28(5): 744–753
13	Chen M, Yi Q T, Hong J J, Zhang L M, Lin K D, Yuan D X. Simultaneous determination of 32 antibiotics and 12 pesticides in sediment using ultrasonic-assisted extraction and high performance liquid chromatography-tandem mass spectrometry. Analytical Methods, 2015, 7(5): 1896–1905 https://doi.org/10.1039/C4AY02895C
14	Chen Z F, Ying G G, Lai H J, Chen F, Su H C, Liu Y S, Peng F Q, Zhao J L. Determination of biocides in different environmental matrices by use of ultra-high-performance liquid chromatography-tandem mass spectrometry. Analytical and Bioanalytical Chemistry, 2012, 404(10): 3175–3188 https://doi.org/10.1007/s00216-012-6444-2 pmid: 23052884
15	Hu X, He K, Zhou Q. Occurrence, accumulation, attenuation and priority of typical antibiotics in sediments based on long-term field and modeling studies. Journal of Hazardous Materials,2012, 225– 226: 91–98 pmid: 22621879
16	Huang Q, Wang Z, Wang C, Peng X. Chiral profiling of azole antifungals in municipal wastewater and recipient rivers of the Pearl River Delta, China. Environmental Science and Pollution Research International, 2013, 20(12): 8890–8899 https://doi.org/10.1007/s11356-013-1862-z pmid: 23749368
17	Huang S, Zhu F, Jiang R, Zhou S, Zhu D, Liu H, Ouyang G. Determination of eight pharmaceuticals in an aqueous sample using automated derivatization solid-phase microextraction combined with gas chromatography-mass spectrometry. Talanta, 2015, 136: 198–203 https://doi.org/10.1016/j.talanta.2014.11.071 pmid: 25703003
18	Liang X, Chen B, Nie X, Shi Z, Huang X, Li X. The distribution and partitioning of common antibiotics in water and sediment of the Pearl River Estuary, South China. Chemosphere, 2013, 92(11): 1410–1416 https://doi.org/10.1016/j.chemosphere.2013.03.044 pmid: 23628172
19	Shi H, Yang Y, Liu M, Yan C, Yue H, Zhou J. Occurrence and distribution of antibiotics in the surface sediments of the Yangtze Estuary and nearby coastal areas. Marine Pollution Bulletin, 2014, 83(1): 317–323 https://doi.org/10.1016/j.marpolbul.2014.04.034 pmid: 24820640
20	Shi X, Zhou J L, Zhao H, Hou L, Yang Y. Application of passive sampling in assessing the occurrence and risk of antibiotics and endocrine disrupting chemicals in the Yangtze Estuary, China. Chemosphere, 2014, 111: 344–351 https://doi.org/10.1016/j.chemosphere.2014.03.139 pmid: 24997938
21	Song H, Zeng X, Yu Z, Zhang D, Cao S, Shao W, Sheng G, Fu J. Enantiomeric composition of polycyclic musks in sediments from the Pearl River and Suzhou Creek. Environmental Science and Pollution Research International, 2015, 22(3): 1679–1686 https://doi.org/10.1007/s11356-014-3687-9 pmid: 25318417
22	Xu W, Yan W, Li X, Zou Y, Chen X, Huang W, Miao L, Zhang R, Zhang G, Zou S. Antibiotics in riverine runoff of the Pearl River Delta and Pearl River Estuary, China: concentrations, mass loading and ecological risks. Environmental Pollution, 2013, 182(6): 402–407 https://doi.org/10.1016/j.envpol.2013.08.004 pmid: 23995020
23	Zhang X, Zhang D, Zhang H, Luo Z, Yan C. Occurrence, distribution, and seasonal variation of estrogenic compounds and antibiotic residues in Jiulongjiang River, South China. Environmental Science and Pollution Research International, 2012, 19(5): 1392–1404 https://doi.org/10.1007/s11356-012-0818-z pmid: 22743989
24	Yang X, Chen F, Meng F, Xie Y, Chen H, Young K, Luo W, Ye T, Fu W. Occurrence and fate of PPCPs and correlations with water quality parameters in urban riverine waters of the Pearl River Delta, South China. Environmental Science and Pollution Research International, 2013, 20(8): 5864–5875 https://doi.org/10.1007/s11356-013-1641-x pmid: 23608973
25	Ma R, Wang B, Lu S, Zhang Y, Yin L, Huang J, Deng S, Wang Y, Yu G. Characterization of pharmaceutically active compounds in Dongting Lake, China: occurrence, chiral profiling and environmental risk. Science of the Total Environment, 2016, 557– 558: 268–275 https://doi.org/10.1016/j.scitotenv.2016.03.053 pmid: 27016674
26	Wang B, Dai G, Deng S, Huang J, Wang Y, Yu G. Linking the environmental loads to the fate of PPCPs in Beijing: considering both the treated and untreated wastewater sources. Environmental Pollution, 2015, 202: 153–159 https://doi.org/10.1016/j.envpol.2015.03.030 pmid: 25827690
27	Dai G, Wang B, Fu C, Dong R, Huang J, Deng S, Wang Y, Yu G. Pharmaceuticals and personal care products (PPCPs) in urban and suburban rivers of Beijing, China: occurrence, source apportionment and potential ecological risk. Environmental Science. Processes & Impacts, 2016, 18(4): 445–455 https://doi.org/10.1039/C6EM00018E pmid: 26985863
28	Ma R, Wang B, Yin L, Zhang Y, Deng S, Huang J, Wang Y, Yu G. Characterization of pharmaceutically active compounds in Beijing, China: occurrence pattern, spatiotemporal distribution and its environmental implication. Journal of Hazardous Materials, 2016,doi:10.1016/j.jhazmat.2016.05.030 https://doi.org/10.1016/j.jhazmat.2016.05.030 pmid: 27236837
29	Wang D, Sui Q, Zhao W T, Lu S G, Qiu Z F, Yu G. Pharmaceutical and personal care products in the surface water of China: a review. China Environmental Science, 2014, 59(59): 743–751(in Chinese)
30	Luo Y, Mao D, Rysz M, Zhou Q, Zhang H, Xu L, J J Alvarez P. Trends in antibiotic resistance genes occurrence in the Haihe River, China. Environmental Science & Technology, 2010, 44(19): 7220–7225 https://doi.org/10.1021/es100233w pmid: 20509603
31	Lu Z H, Na G S, Gao H, Wang L J, Bao C G, Yao Z W. Fate of sulfonamide resistance genes in estuary environment and effect of anthropogenic activities. Science of the Total Environment, 2015, 527–528: 429–438
32	Lin L, Yuan K, Liang X, Chen X, Zhao Z, Yang Y, Zou S, Luan T, Chen B. Occurrences and distribution of sulfonamide and tetracycline resistance genes in the Yangtze River Estuary and nearby coastal area. Marine Pollution Bulletin, 2015, 100(1): 304–310 https://doi.org/10.1016/j.marpolbul.2015.08.036 pmid: 26349787
33	Li W, Shi Y, Gao L, Liu J, Cai Y. Occurrence of antibiotics in water, sediments, aquatic plants, and animals from Baiyangdian Lake in North China. Chemosphere, 2012, 89(11): 1307–1315 https://doi.org/10.1016/j.chemosphere.2012.05.079 pmid: 22698376
34	Duan Y P, Dai C M, Zhang Y L, Chen L. Selective trace enrichment of acidic pharmaceuticals in real water and sediment samples based on solid-phase extraction using multi-templates molecularly imprinted polymers. AnalyticaChimicaActa, 2013, 758: 93–100 https://doi.org/10.1016/j.aca.2012.11.010 pmid: 23245900
35	Lu G, Yang X, Li Z, Zhao H, Wang C. Contamination by metals and pharmaceuticals in northern Taihu Lake (China) and its relation to integrated biomarker response in fish. Ecotoxicology (London, England), 2013, 22(1): 50–59 https://doi.org/10.1007/s10646-012-1002-4 pmid: 23053787
36	Zhu S, Chen H, Li J. Sources, distribution and potential risks of pharmaceuticals and personal care products in Qingshan Lake basin, Eastern China. Ecotoxicology and Environmental Safety, 2013, 96(6): 154–159 https://doi.org/10.1016/j.ecoenv.2013.06.033 pmid: 23871206
37	Wei Y M, Zhang Y, Xu J, Guo C S, Li L, Fan W H. Simultaneous quantification of several classes of antibiotics in water, sediments, and fish muscles by liquid chromatography–tandem mass spectrometry. Frontiers of Environmental Science and Engineering, 2014, 8(3): 357–371 https://doi.org/10.1007/s11783-013-0580-6
38	Xu J, Zhang Y, Zhou C B, Guo C S, Wang D M, Du P, Luo Y, Wan J, Meng W. Distribution, sources and composition of antibiotics in sediment, overlying water and pore water from Taihu Lake, China. Science of the Total Environment, 2014, 497–498: 267–273
39	Tong L, Huang S, Wang Y, Liu H, Li M. Occurrence of antibiotics in the aquatic environment of Jianghan Plain, central China. Science of the Total Environment, 2014, 497-498: 180–187 https://doi.org/10.1016/j.scitotenv.2014.07.068 pmid: 25128888
40	Cheng D M, Liu X H, Wang L, Gong W W, Liu G N, Fu W J, Cheng M. Seasonal variation and sediment–water exchange of antibiotics in a shallower large lake in North China. Science of the Total Environment, 2014, 476–477: 266–275
41	Tang J, Shi T, Wu X, Cao H, Li X, Hua R, Tang F, Yue Y. The occurrence and distribution of antibiotics in Lake Chaohu, China: seasonal variation, potential source and risk assessment. Chemosphere, 2015, 122: 154–161 https://doi.org/10.1016/j.chemosphere.2014.11.032 pmid: 25479810
42	Lei X, Lu J, Liu Z, Tong Y, Li S. Concentration and distribution of antibiotics in water-sediment system of Bosten Lake, Xinjiang. Environmental Science and Pollution Research International, 2015, 22(3): 1670–1678 https://doi.org/10.1007/s11356-014-2994-5 pmid: 24809500
43	Zhang R, Zhang G, Zheng Q, Tang J, Chen Y, Xu W, Zou Y, Chen X. Occurrence and risks of antibiotics in the Laizhou Bay, China: impacts of river discharge. Ecotoxicology and Environmental Safety, 2012, 80(2): 208–215 https://doi.org/10.1016/j.ecoenv.2012.03.002 pmid: 22444724
44	Zhang R, Tang J, Li J, Zheng Q, Liu D, Chen Y, Zou Y, Chen X, Luo C, Zhang G. Antibiotics in the offshore waters of the Bohai Sea and the Yellow Sea in China: occurrence, distribution and ecological risks. Environmental Pollution, 2013, 174(5): 71–77 https://doi.org/10.1016/j.envpol.2012.11.008 pmid: 23246749
45	Zheng Q, Zhang R, Wang Y, Pan X, Tang J, Zhang G. Occurrence and distribution of antibiotics in the Beibu Gulf, China: impacts of river discharge and aquaculture activities. Marine Environmental Research, 2012, 78(8): 26–33 https://doi.org/10.1016/j.marenvres.2012.03.007 pmid: 22525825
46	Zhang H, Liu P, Feng Y, Yang F. Fate of antibiotics during wastewater treatment and antibiotic distribution in the effluent-receiving waters of the Yellow Sea, northern China. Marine Pollution Bulletin, 2013, 73(1): 282–290 https://doi.org/10.1016/j.marpolbul.2013.05.007 pmid: 23768979
47	Na G, Fang X, Cai Y, Ge L, Zong H, Yuan X, Yao Z, Zhang Z. Occurrence, distribution, and bioaccumulation of antibiotics in coastal environment of Dalian, China. Marine Pollution Bulletin, 2013, 69(1–2): 233–237 https://doi.org/10.1016/j.marpolbul.2012.12.028 pmid: 23465572
48	Lv M, Sun Q, Hu A, Hou L, Li J, Cai X, Yu C P. Pharmaceuticals and personal care products in a mesoscale subtropical watershed and their application as sewage markers. Journal of Hazardous Materials, 2014, 280: 696–705 https://doi.org/10.1016/j.jhazmat.2014.08.054 pmid: 25232652
49	Yan Q, Gao X, Chen Y P, Peng X Y, Zhang Y X, Gan X M, Zi C F, Guo J S. Occurrence, fate and ecotoxicological assessment of pharmaceutically active compounds in wastewater and sludge from wastewater treatment plants in Chongqing, the Three Gorges Reservoir Area. Science of the Total Environment, 2014, 470– 471(2): 618–630 https://doi.org/10.1016/j.scitotenv.2013.09.032 pmid: 24176710
50	Sui Q, Huang J, Deng S, Chen W, Yu G. Seasonal variation in the occurrence and removal of pharmaceuticals and personal care products in different biological wastewater treatment processes. Environmental Science & Technology, 2011, 45(8): 3341–3348 https://doi.org/10.1021/es200248d pmid: 21428396
51	Sui Q, Wang D, Zhao W T, Huang J, Yu G, Cao X Q, Qiu Z F, Lu S G. Removal of pharmaceutical and personal care products by sequential ultraviolet and ozonation process in a full-scale wastewater treatment plant. Frontiers of Environmental Science and Engineering, 2014, 8(1): 62–68 https://doi.org/10.1007/s11783-013-0518-z
52	Sui Q, Wang D, Zhao W, Huang J, Yu G, Cao X, Qiu Z, Lu S. Pharmaceuticals and consumer products in four wastewater treatment plants in urban and suburb areas of Shanghai. Environmental Science and Pollution Research International, 2015, 22(8): 6086–6094 https://doi.org/10.1007/s11356-014-3793-8 pmid: 25391230
53	Li X W, Shi H C, Li K X, Zhang L, Gan Y P. Occurrence and fate of antibiotics in advanced wastewatertreatment facilities and receiving rivers in Beijing, China. Frontiers of Environmental Science and Engineering, 2014, 8(6): 888–894 https://doi.org/10.1007/s11783-014-0735-0
54	Du J, Fan Y, Qian X. Occurrence and behavior of pharmaceuticals in sewagetreatment plants in eastern China. Frontiers of Environmental Science and Engineering, 2015, 9(4): 725–730 https://doi.org/10.1007/s11783-014-0661-1
55	Xue B, Zhang R, Wang Y, Liu X, Li J, Zhang G. Antibiotic contamination in a typical developing city in south China: occurrence and ecological risks in the Yongjiang River impacted by tributary discharge and anthropogenic activities. Ecotoxicology and Environmental Safety, 2013, 92(3): 229–236 https://doi.org/10.1016/j.ecoenv.2013.02.009 pmid: 23478166
56	Chen Y, Leung K S Y, Wong J W C, Selvam A. Preliminary occurrence studies of antibiotic residues in Hong Kong and Pearl River Delta. Environmental Monitoring and Assessment, 2013, 185(1): 745–754 https://doi.org/10.1007/s10661-012-2589-x pmid: 22396070
57	Zhang X, Li Y, Liu B, Wang J, Feng C, Gao M, Wang L. Prevalence of veterinary antibiotics and antibiotic-resistant Escherichia coli in the surface water of a livestock production region in northern China. PLoS ONE, 2014, 9(11): e111026 https://doi.org/10.1371/journal.pone.0111026 pmid: 25372873
58	Chen K, Zhou J L. Occurrence and behavior of antibiotics in water and sediments from the Huangpu River, Shanghai, China. Chemosphere, 2014, 95(5): 604–612 https://doi.org/10.1016/j.chemosphere.2013.09.119 pmid: 24182403
59	Liu J, Lu G, Xie Z, Zhang Z, Li S, Yan Z. Occurrence, bioaccumulation and risk assessment of lipophilic pharmaceutically active compounds in the downstream rivers of sewage treatment plants. Science of the Total Environment, 2015, 511: 54–62 https://doi.org/10.1016/j.scitotenv.2014.12.033 pmid: 25531589
60	Dai G, Wang B, Huang J, Dong R, Deng S, Yu G. Occurrence and source apportionment of pharmaceuticals and personal care products in the Beiyun River of Beijing, China. Chemosphere, 2015, 119(119C): 1033–1039 https://doi.org/10.1016/j.chemosphere.2014.08.056 pmid: 25303665
61	Jiang L, Hu X, Yin D, Zhang H, Yu Z. Occurrence, distribution and seasonal variation of antibiotics in the Huangpu River, Shanghai, China. Chemosphere, 2011, 82(6): 822–828 https://doi.org/10.1016/j.chemosphere.2010.11.028 pmid: 21131021
62	Chen Z F, Ying G G, Liu Y S, Zhang Q Q, Zhao J L, Liu S S, Chen J, Peng F J, Lai H J, Pan C G. Triclosan as a surrogate for household biocides: an investigation into biocides in aquatic environments of a highly urbanized region. Water Research, 2014, 58(7): 269–279 https://doi.org/10.1016/j.watres.2014.03.072 pmid: 24793342
63	Zhao J L, Ying G G, Liu Y S, Chen F, Yang J F, Wang L. Occurrence and risks of triclosan and triclocarban in the Pearl River system, South China: from source to the receiving environment. Journal of Hazardous Materials, 2010, 179(1–3): 215–222 https://doi.org/10.1016/j.jhazmat.2010.02.082 pmid: 20303651
64	Yang J F, Ying G G, Zhao J L, Tao R, Su H C, Chen F. Simultaneous determination of four classes of antibiotics in sediments of the Pearl Rivers using RRLC-MS/MS. Science of the Total Environment, 2010, 408(16): 3424–3432 https://doi.org/10.1016/j.scitotenv.2010.03.049 pmid: 20451241
65	Yang Y, Fu J, Peng H, Hou L, Liu M, Zhou J L. Occurrence and phase distribution of selected pharmaceuticals in the Yangtze Estuary and its coastal zone. Journal of Hazardous Materials, 2011, 190(1–3): 588–596 https://doi.org/10.1016/j.jhazmat.2011.03.092 pmid: 21497014
66	Luo Y, Xu L, Rysz M, Wang Y, Zhang H, Alvarez P J J. Occurrence and transport of tetracycline, sulfonamide, quinolone, and macrolide antibiotics in the Haihe River Basin, China. Environmental Science & Technology, 2011, 45(5): 1827–1833 https://doi.org/10.1021/es104009s pmid: 21309601
67	Zhao J L, Zhang Q Q, Chen F, Wang L, Ying G G, Liu Y S, Yang B, Zhou L J, Liu S, Su H C, Zhang R Q. Evaluation of triclosan and triclocarban at river basin scale using monitoring and modeling tools: implications for controlling of urban domestic sewage discharge. Water Research, 2013, 47(1): 395–405 https://doi.org/10.1016/j.watres.2012.10.022 pmid: 23127624
68	Bai Y, Meng W, Xu J, Zhang Y, Guo C. Occurrence, distribution and bioaccumulation of antibiotics in the Liao River Basin in China. Environmental Science. Processes & Impacts, 2014, 16(3): 586–593 https://doi.org/10.1039/c3em00567d pmid: 24509869
69	Kim S C, Carlson K. Quantification of human and veterinary antibiotics in water and sediment using SPE/LC/MS/MS. Analytical and Bioanalytical Chemistry, 2007, 387(4): 1301–1315 https://doi.org/10.1007/s00216-006-0613-0 pmid: 16847620
70	Arikan O A, Rice C, Codling E. Occurrence of antibiotics and hormones in a major agricultural watershed. Desalination, 2008, 226(1–3): 121–133 https://doi.org/10.1016/j.desal.2007.01.238
71	Vazquez-Roig P, Andreu V, Blasco C, Picó Y. Risk assessment on the presence of pharmaceuticals in sediments, soils and waters of the Pego-Oliva Marshlands (Valencia, eastern Spain). Science of the Total Environment, 2012, 440(3): 24–32 https://doi.org/10.1016/j.scitotenv.2012.08.036 pmid: 23021792
72	Matongo S, Birungi G, Moodley B, Ndungu P. Pharmaceutical residues in water and sediment of Msunduzi River, KwaZulu-Natal, South Africa. Chemosphere, 2015, 134: 133–140 https://doi.org/10.1016/j.chemosphere.2015.03.093 pmid: 25935602
73	Zhou J, Broodbank N. Sediment-water interactions of pharmaceutical residues in the river environment. Water Research, 2014, 48(1): 61–70 https://doi.org/10.1016/j.watres.2013.09.026 pmid: 24091188
74	Zhou X F, Dai C M, Zhang Y L, Surampalli R Y, Zhang T C. A preliminary study on the occurrence and behavior of carbamazepine (CBZ) in aquatic environment of Yangtze River Delta, China. Environmental Monitoring and Assessment, 2011, 173(1–4): 45–53 https://doi.org/10.1007/s10661-010-1369-8 pmid: 20213064
75	Wang P H, Yuan T, Hu J Y, Tan Y M. Determination of cephalosporin antibiotics in water samples by optimised solid phase extraction and high performance liquid chromatography with ultraviolet detector. International Journal of Environmental Analytical Chemistry, 2011, 91(13): 1267–1281 https://doi.org/10.1080/03067311003778649
76	Wolf A, Bergmann A, Wilken R D, Gao X, Bi Y, Chen H, Schüth C. Occurrence and distribution of organic trace substances in waters from the Three Gorges Reservoir, China. Environmental Science and Pollution Research International, 2013, 20(10): 7124–7139 https://doi.org/10.1007/s11356-013-1929-x pmid: 23832801
77	Wu C, Huang X, Witter J D, Spongberg A L, Wang K, Wang D, Liu J. Occurrence of pharmaceuticals and personal care products and associated environmental risks in the central and lower Yangtze river, China. Ecotoxicology and Environmental Safety, 2014, 106: 19–26 https://doi.org/10.1016/j.ecoenv.2014.04.029 pmid: 24836873
78	Yan C, Yang Y, Zhou J, Liu M, Nie M, Shi H, Gu L. Antibiotics in the surface water of the Yangtze Estuary: occurrence, distribution and risk assessment. Environmental Pollution, 2013, 175(8): 22–29 https://doi.org/10.1016/j.envpol.2012.12.008 pmid: 23313734
79	Bu Q, Wang B, Huang J, Liu K, Deng S, Wang Y, Yu G. Estimating the use of antibiotics for humans across China. Chemosphere, 2016, 144: 1384–1390 https://doi.org/10.1016/j.chemosphere.2015.10.010 pmid: 26492425
80	Hernando M D, Mezcua M, Fernández-Alba A R, Barceló D. Environmental risk assessment of pharmaceutical residues in wastewater effluents, surface waters and sediments. Talanta, 2006, 69(2): 334–342 https://doi.org/10.1016/j.talanta.2005.09.037 pmid: 18970571
81	Zhang R, Tang J, Li J, Cheng Z, Chaemfa C, Liu D, Zheng Q, Song M, Luo C, Zhang G. Occurrence and risks of antibiotics in the coastal aquatic environment of the Yellow Sea, North China. Science of the Total Environment, 2013, 450– 451(2): 197–204 https://doi.org/10.1016/j.scitotenv.2013.02.024 pmid: 23474265
82	Jiang Y, Li M, Guo C, An D, Xu J, Zhang Y, Xi B. Distribution and ecological risk of antibiotics in a typical effluent-receiving river (Wangyang River) in north China. Chemosphere, 2014, 112: 267–274 https://doi.org/10.1016/j.chemosphere.2014.04.075 pmid: 25048915
83	Li N, Zhang X, Wu W, Zhao X. Occurrence, seasonal variation and risk assessment of antibiotics in the reservoirs in North China. Chemosphere, 2014, 111: 327–335 https://doi.org/10.1016/j.chemosphere.2014.03.129 pmid: 24997936
84	Gunnarsson L, Jauhiainen A, Kristiansson E, Nerman O, Larsson D G. Evolutionary conservation of human drug targets in organisms used for environmental risk assessments. Environmental Science & Technology, 2008, 42(15): 5807–5813 https://doi.org/10.1021/es8005173 pmid: 18754513
85	Wang B, Huang J, Deng S B, Yang X L, Yu G. Addressing the environmental risk of persistent organic pollutants in China. Frontiers of Environmental Science and Engineering, 2012, 6(1): 2–16 https://doi.org/10.1007/s11783-011-0370-y
86	Backhaus T, Faust M. Predictive environmental risk assessment of chemical mixtures: a conceptual framework. Environmental Science & Technology, 2012, 46(5): 2564–2573 https://doi.org/10.1021/es2034125 pmid: 22260322
87	Wen Z H, Chen L, Meng X Z, Duan Y P, Zhang Z S, Zeng E Y. Occurrence and human health risk of wastewater-derived pharmaceuticals in a drinking water source for Shanghai, East China. Science of the Total Environment, 2014, 490: 987–993 https://doi.org/10.1016/j.scitotenv.2014.05.087 pmid: 24914528

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