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High salt and fat intake, inflammation, and risk of cancer |
Amir Abdoli() |
Department of Parasitology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran |
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Abstract BACKGROUND: Inflammatory conditions are involved in the pathophysiology of cancer. Recent findings have revealed that excessive salt and fat intake is involved in the development of severe inflammatory reactions. METHODS: A literature search was performed on various online databases (PubMed, Scopus, and Google Scholar) regarding the roles of high salt and fat intake in the induction of inflammatory reactions and their roles in the etiopathogenesis of cancer. RESULTS: The results indicate that high salt and fat intake can induce severe inflammatory conditions. However, various inflammatory conditions have been strongly linked to the development of cancer. Hence, high salt and fat intake might be involved in the pathogenesis of cancer progression via putative mechanisms related to inflammatory reactions. CONCLUSION: Reducing salt and fat intake may decrease the risk of cancer.
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Keywords
cancer
inflammation
nutrition
salt
fat
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Corresponding Author(s):
Amir Abdoli
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Online First Date: 18 December 2017
Issue Date: 10 January 2018
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