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The influence of HF treatment on corrosion resistance
and in vitro biocompatibility of
Mg-Zn-Zr alloy |
| Xin-Yu YE1,Min-Fang CHEN1,Chen YOU2,De-Bao LIU3, |
| 1.School of Materials
Science and Engineering, Tianjin University of Technology, Tianjin
300384, China; 2.School of Materials
Science and Engineering, Tianjin University of Technology, Tianjin
300384, China；Tianjin Key Laboratory
of Photoelectric Materials and Devices, Tianjin University of Technology,
Tianjin 300384, China; 3.School of Materials
Science and Engineering, Tianjin University of Technology, Tianjin
300384, China；Key Laboratory of Display
Materials and Photoelectric Device (Ministry of Education), Tianjin
University of Technology, Tianjin 300384, China; |
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Abstract The samples made of a Mg-2.5wt.%Zn- 0.5wt.%Zr alloy were immersed in the 20% hydrofluoric acid (HF) solution at room temperature for different time, with the aim of improving the properties of magnesium (Mg) alloy in applications as biomaterials. The corrosion resistance and in vitro biocompatibility of untreated and fluoride-coated samples were investigated. The results show that the optimum process is to immerse Mg alloys in the 20% HF solution for 6h. After the immersion, a dense magnesium fluoride (MgF2) coating of 0.5 mm was synthesized on the surface of Mg-Zn-Zr alloy. Polarization tests recorded a reduction in the corrosion current density from 2.10 to 0.05 mA/cm2 due to the MgF2 protective coating. Immersion tests in the simulated body fluid (SBF) also reveal a much milder corrosion on the fluoride-coated samples, and its corrosion rate was calculated to be 0.05 mm/yr. Hemolysis test suggests that the conversion coated Mg alloy has no obvious hemolysis reaction. The hemolysis ratio (HR) of the samples decreases from 11.34% to 1.86% with the HF treatment, which meets the requirements of biomaterials (HR<5%). The coculture of 3T3 fibroblasts with Mg alloy results in the adhesion and proliferation of cells on the surface of fluoride-coated samples. All the results show that the MgF2 conversion coating would markedly improve the corrosion resistance and in vitro biocompatibility of Mg-Zn-Zr alloy.
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| Keywords
Mg-Zn-Zr Alloy
hydrofluoric acid (HF)
corrosion resistance
in vitro biocompatibility
biomaterials
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Issue Date: 05 June 2010
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